SCHEMBL9318569

SCHEMBL9318569

O=C(O)c1cc(C(=O)O)c(O)cn1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 13/20 0.62
ASPH Q12797 11/20 0.62
KDM8 Q8N371 10/20 0.62
RIOX2 Q8IUF8 8/20 0.46
DDT P30046 1/20 0.44
CA1 P00915 2/20 0.43
CA2 P00918 2/20 0.43
PTGS2 P35354 2/20 0.43
CA12 O43570 1/20 0.43
ALOX5 P09917 1/20 0.43
CA7 P43166 1/20 0.43
CA9 Q16790 1/20 0.43
CA14 Q9ULX7 1/20 0.43
P4HA1 P13674 1/20 0.42
MIF P14174 1/20 0.42
P4HTM Q9NXG6 1/20 0.42
EGLN1 Q9GZT9 2/20 0.41
ALDH1A1 P00352 4/20 0.41
MEN1 O00255 2/20 0.41
KDR P35968 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15793363 0.83 KDM4E (0.57) KDM4EASPHKDM8RIOX2DDT
SCHEMBL1171098 0.82 KDM4E (0.67) KDM4EASPHKDM8RIOX2DDT
SCHEMBL5263152 0.82 KDM4E (0.50) KDM4EASPHKDM8RIOX2DDT
SCHEMBL23854026 0.80 CA1 (0.45) KDM4EASPHKDM8CA1CA2
SCHEMBL13360236 0.80 CA1 (0.45) KDM4EASPHKDM8CA1CA2
Water SCHEMBL9013414 0.80 KDM4E (0.48) KDM4EASPHKDM8RIOX2DDT
SCHEMBL7018427 0.77 CSNK2A1 (0.48) KDM4ECA1CA2PTGS2CA12
SCHEMBL21246826 0.77 CA1 (0.42) KDM4EASPHKDM8CA1CA2
SCHEMBL20855918 0.77 CA1 (0.48) KDM4EASPHKDM8CA1CA2
SCHEMBL5917874 0.77 KDM4E (0.46) KDM4EASPHKDM8DDTPTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10590343-B2 Corrosion inhibitor composition for magnesium or magnesium alloys Helmholtz-Zentrum Geesthacht Zentrum für Material-und Küstenforschung GmbH (DE) 2020-03-17 US claimed
EP-3284847-B1 CORROSION INHIBITOR COMPOSITION FOR MAGNESIUM OR MAGNESIUM ALLOYS HELMHOLTZ ZENTRUM GEESTHACHT (DE) 2019-01-02 EP claimed
EP-3284847-A1 CORROSION INHIBITOR COMPOSITION FOR MAGNESIUM OR MAGNESIUM ALLOYS Helmholtz-Zentrum Geesthacht Zentrum für Material- und Küstenforschung GmbH (DE) 2018-02-21 EP claimed
US-20180044590-A1 Corrosion Inhibitor Composition for Magnesium or Magnesium Alloys Helmholtz-Zentrum Geesthacht Zentrum für Material-und Küstenforschung GmbH (DE) 2018-02-15 US claimed
US-10590343-B2 Corrosion inhibitor composition for magnesium or magnesium alloys Helmholtz-Zentrum Geesthacht Zentrum für Material-und Küstenforschung GmbH (DE) 2020-03-17 US disclosed
EP-3284847-B1 CORROSION INHIBITOR COMPOSITION FOR MAGNESIUM OR MAGNESIUM ALLOYS HELMHOLTZ ZENTRUM GEESTHACHT (DE) 2019-01-02 EP disclosed
EP-3284847-A1 CORROSION INHIBITOR COMPOSITION FOR MAGNESIUM OR MAGNESIUM ALLOYS Helmholtz-Zentrum Geesthacht Zentrum für Material- und Küstenforschung GmbH (DE) 2018-02-21 EP disclosed
US-20180044590-A1 Corrosion Inhibitor Composition for Magnesium or Magnesium Alloys Helmholtz-Zentrum Geesthacht Zentrum für Material-und Küstenforschung GmbH (DE) 2018-02-15 US disclosed
US-5356909-A Substituted pyridine-2,4-dicarboxylic acid compounds and the use thereof and medicaments HOECHST AKTIENGESELLSCHAFT (DE) 1994-10-18 US disclosed
EP-0281943-B1 Substituted pyridine-2,4-carboxylic acid derivatives, process for their preparation, their use as well as medicaments based on these compounds HOECHST AG (DE) 1994-01-12 EP disclosed
US-5143926-A Substituted pyridine-2,4-dicarboxylic acid compounds and methods of use thereof HOECHST AKTIENGESELLSCHAFT (DE) 1992-09-01 US disclosed
US-5004748-A Substituted pyridine-2,4-dicarboxylic acid derivatives and medicaments based on these compounds HOECHST AKTIENGESELLSCHAFT (DE) 1991-04-02 US disclosed
EP-0281943-A2 Substituted pyridine-2,4-carboxylic acid derivatives, process for their preparation, their use as well as medicaments based on these compounds HOECHST AKTIENGESELLSCHAFT (DE) 1988-09-14 EP disclosed