Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5362222 | 0.89 | HCAR3 (0.49) | FGFR1HPGDHCAR3ALDH1A1LMNA | |
| SCHEMBL31744961 | 0.87 | FGFR1 (0.40) | FGFR1KDM4EHPGDMAPTALDH1A1 | |
| SCHEMBL5364346 | 0.78 | TP53 (0.52) | KDM4EHPGDMAPTALDH1A1LMNA | |
| SCHEMBL5358234 | 0.77 | LMNA (0.48) | HPGDLMNAMEN1MAPK1KMT2A | |
| SCHEMBL796768 | 0.76 | NPM1 (0.43) | HPGDMAPTALDH1A1LMNAHSD17B10 | |
| SCHEMBL31613927 | 0.75 | FGFR1 (0.50) | FGFR1KDM4EHPGDHCAR3ALDH1A1 | |
| SCHEMBL5352150 | 0.73 | ALDH1A1 (0.55) | HPGDALDH1A1MAPK1 | |
| SCHEMBL10733133 | 0.72 | KDM4E (0.55) | FGFR1KDM4EHPGDMAPTHCAR3 | |
| SCHEMBL31325815 | 0.72 | KDM4E (0.53) | KDM4EMAPTALDH1A1LMNAHSD17B10 | |
| SCHEMBL29892764 | 0.70 | HPGD (0.47) | FGFR1KDM4EHPGDMAPTHCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118359617-A | Protein arginine methyltransferase inhibitors | 华润医药研究院（深圳）有限公司 | 2024-07-19 | — | — | CN | disclosed |
| US-7202245-B2 | Substituted 4-amino[1,2,4]triazolo[4,3-a] quinoxalines | PFIZER INC. (US) | 2007-04-10 | — | — | US | disclosed |