Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 14/20 | 0.57 |
| ▸ | CASP2 | P42575 | 3/20 | 0.57 |
| ▸ | CASP7 | P55210 | 3/20 | 0.57 |
| ▸ | CASP6 | P55212 | 3/20 | 0.57 |
| ▸ | CASP8 | Q14790 | 3/20 | 0.57 |
| ▸ | TLK2 | Q86UE8 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.47 |
| ▸ | FLT1 | P17948 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5529117 | 0.76 | GSK3B (0.60) | CASP3ALDH1A1HPGD | |
| SCHEMBL13442874 | 0.73 | CASP3 (1.00) | CASP3CASP2CASP7CASP6CASP8 | |
| Sulfuric Acid SCHEMBL5520060 | 0.72 | GSK3B (0.56) | CASP3ALDH1A1 | |
| SCHEMBL29111180 | 0.72 | TGM2 (0.56) | CASP3ALDH1A1 | |
| SCHEMBL6820003 | 0.70 | POLB (0.64) | ALDH1A1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL5740929 | 0.69 | GSK3B (0.48) | CASP3ALDH1A1 | |
| SCHEMBL22079624 | 0.68 | POLB (0.51) | HPGD | |
| SCHEMBL32682829 | 0.68 | PAK1 (0.66) | ALDH1A1PAK1 | |
| SCHEMBL13442881 | 0.68 | CASP3 (1.00) | CASP3CASP2CASP7CASP6CASP8 | |
| SCHEMBL6820154 | 0.67 | ALDH1A1 (0.60) | ALDH1A1HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007132280-A1 | ISATIN AND ITS DERIVATIVES FOR USE AS A MEDICAMENT | Szegedi Tudományegyetem (HU) | 2007-11-22 | — | — | WO | disclosed |