SCHEMBL5359633

SCHEMBL5359633

COCCCO[Si](OCCCOC)(c1ccccc1)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KCNH3 Q9ULD8 2/20 0.41
ALDH1A1 P00352 6/20 0.41
MAPK1 P28482 2/20 0.39
POLB P06746 2/20 0.36
TDP1 Q9NUW8 2/20 0.36
CA2 P00918 1/20 0.35
KDM4E B2RXH2 2/20 0.35
LMNA P02545 1/20 0.35
KMT2A Q03164 3/20 0.34
HPGD P15428 2/20 0.34
NCF1 P14598 2/20 0.34
GAA P10253 1/20 0.34
APOBEC3G Q9HC16 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
MEN1 O00255 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
DUT P33316 1/20 0.33
GLA P06280 1/20 0.33
KCNA3 P22001 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5363348 0.88 CA2 (0.41) KCNH3ALDH1A1MAPK1POLBTDP1
SCHEMBL8678984 0.84 MAPK1 (0.39) KCNH3ALDH1A1MAPK1POLBTDP1
SCHEMBL23521387 0.82 CA2 (0.38) KCNH3ALDH1A1POLBTDP1CA2
SCHEMBL431558 0.82 LTA4H (0.47) ALDH1A1MAPK1TDP1
SCHEMBL702280 0.80 LTA4H (0.46) ALDH1A1MAPK1TDP1
SCHEMBL2834685 0.80 LTA4H (0.47) ALDH1A1MAPK1LMNASMN1; SMN2KCNA3
SCHEMBL11364614 0.78 LTA4H (0.46) ALDH1A1MAPK1LMNAKMT2ASMN1; SMN2
SCHEMBL8665990 0.78 LTA4H (0.46) ALDH1A1MAPK1LMNAKMT2ASMN1; SMN2
SCHEMBL28808583 0.78 MEN1 (0.36) KCNH3ALDH1A1MAPK1POLBTDP1
SCHEMBL24312364 0.78 SMN1; SMN2 (0.40) KCNH3ALDH1A1MAPK1POLBTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7193026-B2 Organosilicon compound-curing composition and silicone-base coating composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 2007-03-20 US disclosed
US-20040260048-A1 Organosilicon compound - curing composition and silicone-base coating composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 2004-12-23 US disclosed