SCHEMBL535984

SCHEMBL535984

[CH2]COc1ccc(OC)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.58
CA2 P00918 2/20 0.58
CA7 P43166 2/20 0.58
CA9 Q16790 2/20 0.58
CA12 O43570 1/20 0.58
CA14 Q9ULX7 1/20 0.58
ACHE P22303 1/20 0.48
APP P05067 3/20 0.47
TSHR P16473 2/20 0.46
ALDH1A1 P00352 2/20 0.46
CYP3A4 P08684 2/20 0.46
TP53 P04637 1/20 0.46
ALOX15 P16050 1/20 0.46
ALOX12 P18054 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
IDO1 P14902 1/20 0.46
TDP1 Q9NUW8 3/20 0.46
MAPK1 P28482 2/20 0.46
CYP2C9 P11712 1/20 0.45
MAOB P27338 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4707838 0.86 NQO1 (0.47) CA1CA2CA7CA9CA12
SCHEMBL72510 0.80 CA12 (0.52) CA1CA2CA7CA9CA12
SCHEMBL3166151 0.79 ALDH1A1 (0.58) CA1CA2CA7CA9CA12
SCHEMBL9664138 0.79 NQO1 (0.74) CA1CA2CA7CA9CA12
SCHEMBL426483 0.79 DRD2 (0.48) ACHETDP1MAOBMAPTL3MBTL1
SCHEMBL1047649 0.78 DRD2 (0.52) CA1CA2CA7CA9CA12
SCHEMBL1343630 0.78 CA12 (0.65) CA1CA2CA7CA9CA12
SCHEMBL10637391 0.78 CA1 (0.65) CA1CA2CA7CA9CA12
SCHEMBL535412 0.77 MAOB (0.58) CA1CA2CA7CA9ACHE
SCHEMBL1044851 0.77 MAPT (0.53) CA1CA2CA7CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 273 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3172259-B1 NOVEL POLYMERS CONTAINING SULPHONAMIDE SODIUM OR LITHIUM SALTS, PRODUCTION METHODS THEREOF AND USES OF SAME AS ELECTROLYTES FOR BATTERIES CDP INNOVATION (FR) 2021-05-19 EP claimed
CN-106754853-B Irreversible affinity labeling reagent for labeling GST and application 重庆医科大学 2020-02-04 CN claimed
CN-107004455-B New polymers, preparation method containing sulfonamide sodium or lithium salts and its purposes as cell electrolyte CDP创新公司 2019-07-16 CN claimed
US-10109883-B2 Polymers containing sulfonamide sodium or lithium salts, methods for production thereof and uses of same as electrolytes for batteries CPD INNOVATION (FR) 2018-10-23 US claimed
CN-107004455-A New polymers, its preparation method containing sulfonamide sodium or lithium salts and its purposes as cell electrolyte CDP创新公司 2017-08-01 CN claimed
US-20170170516-A1 NOVEL POLYMERS CONTAINING SULFONAMIDE SODIUM OR LITHIUM SALTS, METHODS FOR PRODUCTION THEREOF AND USES OF SAME AS ELECTROLYTES FOR BATTERIES CDP INNOVATION (FR) 2017-06-15 US claimed
EP-2200440-A1 ANTIBACTERIAL AMIDE AND SULFONAMIDE SUBSTITUTED HETEROCYCLIC UREA COMPOUNDS Crestone, Inc. (US) 2010-06-30 EP claimed
US-7671089-B2 Levodopa prodrugs, and compositions and uses thereof XENOPORT, INC. (US) 2010-03-02 US claimed
US-20100004332-A1 Levodopa Prodrugs, and Compositions and Uses Thereof XENOPORT, INC. (US) 2010-01-07 US claimed
WO-2009015208-A1 ANTIBACTERIAL AMIDE AND SULFONAMIDE SUBSTITUTED HETEROCYCLIC UREA COMPOUNDS REPLIDYNE, INC. (US) 2009-01-29 WO claimed
EP-0766665-A2 METALLOPROTEINASE INHIBITORS BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) 1997-04-09 EP claimed
WO-1995035276-A1 METALLOPROTEINASE INHIBITORS BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) 1995-12-28 WO claimed
WO-1995035275-A1 METALLOPROTEINASE INHIBITORS BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) 1995-12-28 WO claimed
EP-0159584-B1 N-(AZOLYLCARBAMOYL)-HYDROXYL AMINES AND FUNGICIDES CONTAINING THEM BASF Aktiengesellschaft (DE) 1989-01-18 EP claimed
US-4689411-A ANTIBIOTICS OTSUKA KAGAKU YAKUHIN KABUSHIKI KAISHA (JP) 1987-08-25 US claimed
US-4678798-A PLANTS, SEEDS BASF AKTIENGESELLSCHAFT (DE) 1987-07-07 US claimed
EP-0159584-A2 N-(azolylcarbamoyl)-hydroxyl amines and fungicides containing them BASF Aktiengesellschaft (DE) 1985-10-30 EP claimed
US-4252716-A BLUE SHADES BAYER AKTIENGESELLSCHAFT (DE) 1981-02-24 US claimed
US-4000141-A SUBSTITUTED TETRAHYDRO QUINOLINE CATIONIC DYESTUFFS BAYER AKTIENGESELLSCHAFT (DT) 1976-12-28 US claimed
US-3991042-A Basic azo dyestuffs containing a benzthiazole and a tetrahydroquinoline nucleus BAYER AKTIENGESELLSCHAFT (DT) 1976-11-09 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100004332-A1 Levodopa Prodrugs, and Compositions and Uses Thereof COMT, DDT, DDC CA1 3469/4885CA2 4601/4885CA7 3171/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.