Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP6V1B1 | P15313 | 1/20 | 0.51 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 2/20 | 0.41 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GABRP | O00591 | 1/20 | 0.40 |
| ▸ | GABRD | O14764 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5360579 | 1.00 | ATP6V1B1 (0.51) | ATP6V1B1CYP2A6MAPTCYP2C19IDO1 | |
| SCHEMBL5313959 | 0.84 | ATP6V1B1 (0.61) | ATP6V1B1CYP2A6MAPTCYP2C19IDO1 | |
| SCHEMBL12809345 | 0.84 | ATP6V1B1 (0.61) | ATP6V1B1CYP2A6MAPTCYP2C19IDO1 | |
| SCHEMBL30407949 | 0.84 | FLT3 (0.43) | MAPTCYP2C19CYP1A2PDGFRBPDGFRA | |
| SCHEMBL1072201 | 0.81 | KDM4E (0.58) | CYP1A2PDGFRBPDGFRAFLT3KDM4E | |
| SCHEMBL1072204 | 0.81 | KDM4E (0.58) | CYP1A2PDGFRBPDGFRAFLT3KDM4E | |
| SCHEMBL2239744 | 0.81 | ATP6V1B1 (0.51) | ATP6V1B1CYP2A6MAPTCYP2C19IDO1 | |
| SCHEMBL2239741 | 0.81 | ATP6V1B1 (0.51) | ATP6V1B1CYP2A6MAPTCYP2C19IDO1 | |
| SCHEMBL13229465 | 0.79 | CYP2A6 (0.56) | ATP6V1B1CYP2A6MAPTCYP2C19IDO1 | |
| SCHEMBL5355906 | 0.78 | MTNR1A (0.43) | MAPTIDO1FLT3KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007134421-A1 | 2-VINYL INDOLES, PYRIDO AND AZEPINO INDOLE DERIVATIVES, 2-ALKYNYL INDOLES, 2-ALKYNYL BENZO[b]FURANS, THEIR PRECURSORS AND NOVEL PROCESSES FOR THE PREPARATION THEREOF | LAUTENS MARK (CA) | 2007-11-29 | — | — | WO | disclosed |