Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.42 |
| ▸ | FLT3 | P36888 | 2/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | ITK | Q08881 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5355901 | 1.00 | MTNR1A (0.43) | MTNR1AMTNR1BHRH4FLT3IDO1 | |
| SCHEMBL5360581 | 0.78 | ATP6V1B1 (0.51) | FLT3IDO1KDM4EDRD3MAPT | |
| SCHEMBL5360579 | 0.78 | ATP6V1B1 (0.51) | FLT3IDO1KDM4EDRD3MAPT | |
| SCHEMBL26611680 | 0.76 | ABCG2 (0.59) | KDM4EALDH1A1ESR1MAPTSMN1; SMN2 | |
| SCHEMBL24557535 | 0.76 | ABCG2 (0.59) | KDM4EALDH1A1ESR1MAPTSMN1; SMN2 | |
| SCHEMBL20920169 | 0.74 | ALDH1A1 (0.49) | MTNR1AMTNR1BHRH4FLT3IDO1 | |
| SCHEMBL19244392 | 0.72 | NFE2L2 (0.66) | KDM4EALDH1A1MEN1MAPTHPGD | |
| SCHEMBL19244393 | 0.72 | NFE2L2 (0.66) | KDM4EALDH1A1MEN1MAPTHPGD | |
| SCHEMBL20937296 | 0.71 | ITK (0.44) | MTNR1AMTNR1BHRH4FLT3IDO1 | |
| SCHEMBL30407949 | 0.71 | FLT3 (0.43) | HRH4FLT3KDM4EALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007134421-A1 | 2-VINYL INDOLES, PYRIDO AND AZEPINO INDOLE DERIVATIVES, 2-ALKYNYL INDOLES, 2-ALKYNYL BENZO[b]FURANS, THEIR PRECURSORS AND NOVEL PROCESSES FOR THE PREPARATION THEREOF | LAUTENS MARK (CA) | 2007-11-29 | — | — | WO | disclosed |