Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.38 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | EP300 | Q09472 | 1/20 | 0.35 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.35 |
| ▸ | SLC11A2 | P49281 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL535437 | 0.80 | HDAC8 (0.43) | SMN1; SMN2ALDH1A1MAPTKDM4EPLD1 | |
| SCHEMBL535473 | 0.79 | TDP1 (0.42) | SMN1; SMN2ALDH1A1CD274PDCD1KDM4E | |
| SCHEMBL535560 | 0.79 | SMN1; SMN2 (0.37) | SMN1; SMN2ALDH1A1MAPTKDM4EPLD1 | |
| SCHEMBL535554 | 0.79 | SMN1; SMN2 (0.37) | SMN1; SMN2ALDH1A1KDM4EPLD1GAA | |
| SCHEMBL16739280 | 0.78 | SMN1; SMN2 (0.41) | SMN1; SMN2L3MBTL1ALDH1A1CD274PDCD1 | |
| SCHEMBL536282 | 0.75 | HTT (0.37) | SMN1; SMN2ALDH1A1CD274PDCD1MAPT | |
| SCHEMBL356155 | 0.73 | MAPK1 (0.40) | SMN1; SMN2ALDH1A1MAPTKDM4EGAA | |
| SCHEMBL14635044 | 0.71 | SMN1; SMN2 (0.44) | SMN1; SMN2L3MBTL1ALDH1A1CD274PDCD1 | |
| SCHEMBL535921 | 0.71 | HSD11B1 (0.41) | RAB9A | |
| SCHEMBL535441 | 0.68 | SMN1; SMN2 (0.40) | SMN1; SMN2ALDH1A1KDM4EPLD1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10154995-B2 | Serine/threonine kinase inhibitors | ARRAY BIOPHARMA INC. (US) | 2018-12-18 | — | — | US | claimed |
| EP-3089788-B1 | SERINE/THREONINE KINASE INHIBITORS | GENENTECH INC (US) | 2018-10-24 | — | — | EP | claimed |
| US-20170348310-A1 | SERINE/THREONINE KINASE INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2017-12-07 | — | — | US | claimed |
| US-9763942-B2 | Serine/threonine kinase inhibitors | GENENTECH, INC. (US) | 2017-09-19 | — | — | US | claimed |
| EP-3089788-A1 | SERINE/THREONINE KINASE INHIBITORS | Genentech, Inc. (US) | 2016-11-09 | — | — | EP | claimed |
| US-20160303126-A1 | SERINE/THREONINE KINASE INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2016-10-20 | — | — | US | claimed |
| WO-2015103133-A1 | SERINE/THREONINE KINASE INHIBITORS | GENENTECH, INC. (US) | 2015-07-09 | — | — | WO | claimed |
| US-10154995-B2 | Serine/threonine kinase inhibitors | ARRAY BIOPHARMA INC. (US) | 2018-12-18 | — | — | US | disclosed |
| EP-3089788-B1 | SERINE/THREONINE KINASE INHIBITORS | GENENTECH INC (US) | 2018-10-24 | — | — | EP | disclosed |
| US-20170348310-A1 | SERINE/THREONINE KINASE INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2017-12-07 | — | — | US | disclosed |
| US-9763942-B2 | Serine/threonine kinase inhibitors | GENENTECH, INC. (US) | 2017-09-19 | — | — | US | disclosed |
| EP-3089788-A1 | SERINE/THREONINE KINASE INHIBITORS | Genentech, Inc. (US) | 2016-11-09 | — | — | EP | disclosed |
| US-20160303126-A1 | SERINE/THREONINE KINASE INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2016-10-20 | — | — | US | disclosed |
| US-20110071291-A1 | HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME | IKEGAMI HIROSHI | 2011-03-24 | — | — | US | disclosed |
| US-7867949-B2 | Hydrazide compound and pesticidal use of the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-01-11 | — | — | US | disclosed |
| EP-2251336-A1 | Hydrazide compounds as intermediates of pesticides | Sumitomo Chemical Company, Limited (JP) | 2010-11-17 | — | — | EP | disclosed |
| US-20100137314-A1 | HARMFUL ORGANISM CONTROL COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-06-03 | — | — | US | disclosed |
| US-20100137362-A1 | HETEROCYCLIC HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-06-03 | — | — | US | disclosed |
| US-20100099692-A1 | HARMFUL ORGANISM CONTROL COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-04-22 | — | — | US | disclosed |
| US-20090181956-A1 | Hydrazide Compound and Pesticidal Use of the Same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160303126-A1 | SERINE/THREONINE KINASE INHIBITORS | MAP3K1, TTBK1, MAP3K11 | SMN1; SMN2 746/4885L3MBTL1 1885/4885ALDH1A1 3719/4885 |
| US-20100099692-A1 | HARMFUL ORGANISM CONTROL COMPOSITION | UQCRC1, UQCRC2, Q6ZSR9 | SMN1; SMN2 3015/4885L3MBTL1 5/4885ALDH1A1 280/4885 |
| US-10154995-B2 | Serine/threonine kinase inhibitors | MAP3K1, TTBK1, MAP3K11 | SMN1; SMN2 746/4885L3MBTL1 1885/4885ALDH1A1 3719/4885 |
| US-20110071291-A1 | HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME | ACHE, H1-2, H1-0 | SMN1; SMN2 2851/4885L3MBTL1 852/4885ALDH1A1 238/4885 |
| US-20100137314-A1 | HARMFUL ORGANISM CONTROL COMPOSITION | UQCRC2, UQCRC1, UQCRB | SMN1; SMN2 3145/4885L3MBTL1 6/4885ALDH1A1 217/4885 |
| US-20170348310-A1 | SERINE/THREONINE KINASE INHIBITORS | MAP3K1, TTBK1, MAP3K11 | SMN1; SMN2 746/4885L3MBTL1 1885/4885ALDH1A1 3719/4885 |
| US-20090181956-A1 | Hydrazide Compound and Pesticidal Use of the Same | ACHE, DDT, CAT | SMN1; SMN2 2755/4885L3MBTL1 2293/4885ALDH1A1 436/4885 |
| US-20100137362-A1 | HETEROCYCLIC HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME | ACHE, CAT, DNPH1 | SMN1; SMN2 2564/4885L3MBTL1 3467/4885ALDH1A1 719/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.