SCHEMBL5361409

SCHEMBL5361409

CCC(c1ccc(C)cc1)[Si](OC)(OC)OC

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.38
LMNA P02545 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
CHRNA7 P36544 1/20 0.34
ACHE P22303 3/20 0.33
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
CYP19A1 P11511 3/20 0.33
MAPT P10636 1/20 0.33
TDP1 Q9NUW8 1/20 0.32
MLKL Q8NB16 1/20 0.31
CYP17A1 P05093 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17442501 0.92 CYP17A1 (0.34) LMNACYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL28324268 0.82 TDP1 (0.36) ALDH1A1LMNAMEN1KMT2ACYP1A2
SCHEMBL5048126 0.82 FAAH (0.32) ALDH1A1CYP17A1
SCHEMBL17888500 0.82 ESR1 (0.50) LMNACYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL2822248 0.82 LMNA (0.43) LMNAMEN1KMT2A
SCHEMBL20238791 0.78 ALDH1A1 (0.38) ALDH1A1CHRNA7
SCHEMBL3789520 0.77 MAPT (0.44) ALDH1A1SMN1; SMN2KMT2AMAPT
SCHEMBL15209649 0.76 LMNA (0.33) LMNAACHE
SCHEMBL7916771 0.75 PBRM1 (0.35) ALDH1A1LMNACYP17A1
SCHEMBL25285956 0.75 ESR1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7202019-B2 Photothermographic imaging material KONICA MINOLTA HOLDINGS, INC. (JP) 2007-04-10 US disclosed
US-7115359-B2 Photothermographic material KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2006-10-03 US disclosed
US-20050037298-A1 Photothermographic material KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2005-02-17 US disclosed
EP-1500973-A2 Photothermographic material Konica Minolta Medical & Graphic, Inc. (JP) 2005-01-26 EP disclosed
US-6808872-B2 CONCERNS IN PROCESSING OF PHOTOGRAPHIC FILM WITH RESPECT TO EFFLUENT PRODUCED FROM WET-PROCESSING OF IMAGE-FORMING MATERIALS, AND RECENTLY, REDUCTION OF THE PROCESSING EFFLUENT IS STRONGLY DEMANDED IN TERMS OF ENVIRONMENTAL PROTECTION AND KONICA CORPORATION (JP) 2004-10-26 US disclosed
US-20040101794-A1 Photothermographic imaging material KONICA MINOLTA HOLDINGS, INC. (JP) 2004-05-27 US disclosed
US-20040005521-A1 Silver salt photothermographic dry imaging material KONICA CORPORATION (JP) 2004-01-08 US disclosed