SCHEMBL536184

SCHEMBL536184

CC1(C)CC(NCc2ccccc2)CC(C)(C)N1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.71
LMNA P02545 2/20 0.71
GAA P10253 2/20 0.71
ALDH1A1 P00352 3/20 0.68
NPSR1 Q6W5P4 1/20 0.68
KMT2A Q03164 3/20 0.60
SLC2A1 P11166 1/20 0.52
MEN1 O00255 1/20 0.51
MAPT P10636 1/20 0.51
PKM P14618 1/20 0.51
ALOX15 P16050 1/20 0.51
ALOX12 P18054 1/20 0.51
RAD52 P43351 1/20 0.51
GFER P55789 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
KDM1A O60341 1/20 0.50
GRIN2B Q13224 1/20 0.49
HTT P42858 1/20 0.48
OPRM1 P35372 2/20 0.48
OPRL1 P41146 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL536342 0.91 ALDH1A1 (0.79) KDM4ELMNAGAAALDH1A1NPSR1
SCHEMBL13057548 0.85 ALDH1A1 (0.70) KDM4ELMNAGAAALDH1A1NPSR1
SCHEMBL10638085 0.85 KDM4E (0.54) KDM4ELMNAGAAALDH1A1NPSR1
SCHEMBL9668475 0.83 GAA (0.63) KDM4ELMNAGAAALDH1A1NPSR1
SCHEMBL6900166 0.83 ALDH1A1 (0.68) KDM4ELMNAGAAALDH1A1NPSR1
SCHEMBL11161937 0.78 CARM1 (0.49) KDM4ELMNAGAAALDH1A1NPSR1
SCHEMBL11368731 0.78 KDM4E (0.52) KDM4ELMNAGAAALDH1A1NPSR1
SCHEMBL27260792 0.77 ALDH1A1 (0.48) KDM4ELMNAGAAALDH1A1NPSR1
SCHEMBL6933598 0.77 ACHE (0.46) KDM4ELMNAGAAALDH1A1NPSR1
SCHEMBL6933594 0.77 KDM4E (0.48) KDM4ELMNAGAAALDH1A1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 149 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107207753-B Hard coat film, polarizing plate, liquid crystal display device, and method for producing hard coat film 富士胶片株式会社 2020-12-25 CN disclosed
US-10365411-B2 Hardcoat film, polarizing plate, liquid crystal display, and method for manufacturing hardcoat film FUJIFILM CORPORATION (JP) 2019-07-30 US disclosed
CN-105278009-B Manufacturing method, hard coat film, polarizing film and the liquid crystal display device of hard coat film 富士胶片株式会社 2019-01-29 CN disclosed
CN-105849600-B Optical film, polarizing plate and image display device 柯尼卡美能达株式会社 2018-06-22 CN disclosed
US-9951205-B2 Stable compositions of thiabendazole and iodine-containing fungicides LANXESS DEUTSCHLAND GMBH (DE) 2018-04-24 US disclosed
US-9829606-B2 Method of manufacturing hard coat film, hard coat film, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2017-11-28 US disclosed
US-20170322345-A1 HARDCOAT FILM, POLARIZING PLATE, LIQUID CRYSTAL DISPLAY, AND METHOD FOR MANUFACTURING HARDCOAT FILM FUJIFILM CORPORATION (JP) 2017-11-09 US disclosed
EP-2413697-B1 STABILISATION OF COMPOUNDS CONTAINING IODINE LANXESS DEUTSCHLAND GMBH (DE) 2017-11-08 EP disclosed
CN-107207753-A Hard-coated film, polarizer, the manufacture method of liquid crystal display device and hard-coated film 富士胶片株式会社 2017-09-26 CN disclosed
CN-103102511-B Cellulose acylate film, protective film for polarizing plate, polarizing plate, and liquid crystal display device 富士胶片株式会社 2017-05-17 CN disclosed
EP-0006564-B1 2-(3.5-DISUBSTITUTED-2-HYDROXYPHENYL)-2H-BENZOTRIAZOLES AND STABILIZED COMPOSITIONS CONTAINING THEM CIBA-GEIGY AG (CH) 1981-12-30 EP disclosed
EP-0034829-A1 Tetra-alkyl-4-amino-piperidine containing acids and corresponding salts and use thereof as stabilizers for polymers Montedison S.p.A. (IT) 1981-09-02 EP disclosed
US-4278589-A 2-[2-Hydroxy-3,5-di-(α,α-dimethylbenzyl)phenyl]-2H-benzotriazole and stabilized compositions CIBA-GEIGY CORPORATION (US) 1981-07-14 US disclosed
US-4278590-A AUTOMOBILE FINISHES CIBA-GEIGY CORPORATION (US) 1981-07-14 US disclosed
EP-0016723-A1 Light stabilisation of two-layer composite lacquers CIBA-GEIGY AG (CH) 1980-10-01 EP disclosed
EP-0015230-A1 Stabilized organic Polymer comprising 2-(2-hydroxy-3,5-di-tert-octylphenyl)-2H-benzotriazole as a light-stabilizer CIBA-GEIGY AG (CH) 1980-09-03 EP disclosed
EP-0006564-A2 2-(3.5-disubstituted-2-hydroxyphenyl)-2H-benzotriazoles and stabilized compositions containing them CIBA-GEIGY AG (CH) 1980-01-09 EP disclosed
EP-0002753-A2 Stabilisation of heat-curable metallic enamel paints against the action of light, humidity and oxygen by the addition of polyalkylpiperidine derivatives CIBA-GEIGY AG (CH) 1979-07-11 EP disclosed
US-4101506-A PIPERIDINE COMPOUNDS, STABILIZERS FOR POLYMERS BAYER AKTIENGESELLSCHAFT (DE) 1978-07-18 US disclosed
US-4088629-A ADDING A PIPERIDINYL-GUANIDINE BAYER AKTIENGESELLSCHAFT (DT) 1978-05-09 US disclosed