SCHEMBL536342

SCHEMBL536342

CC1(C)CC(NCc2ccc(CNC3CC(C)(C)NC(C)(C)C3)cc2)CC(C)(C)N1

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.79
NPSR1 Q6W5P4 1/20 0.79
KDM4E B2RXH2 3/20 0.78
LMNA P02545 2/20 0.78
GAA P10253 2/20 0.78
KMT2A Q03164 4/20 0.57
MEN1 O00255 3/20 0.44
MAPT P10636 2/20 0.44
PKM P14618 1/20 0.44
ALOX15 P16050 1/20 0.44
ALOX12 P18054 1/20 0.44
RAD52 P43351 1/20 0.44
GFER P55789 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
POLB P06746 2/20 0.43
RECQL P46063 1/20 0.43
SLC2A1 P11166 1/20 0.43
HRH3 Q9Y5N1 1/20 0.43
KDM1A O60341 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13057548 0.93 ALDH1A1 (0.70) ALDH1A1NPSR1KDM4ELMNAGAA
SCHEMBL6900166 0.92 ALDH1A1 (0.68) ALDH1A1NPSR1KDM4ELMNAGAA
SCHEMBL536184 0.91 KDM4E (0.71) ALDH1A1NPSR1KDM4ELMNAGAA
SCHEMBL1470643 0.84 ALDH1A1 (0.59) ALDH1A1NPSR1KDM4ELMNAGAA
SCHEMBL13412658 0.76 RAB9A (0.55) ALDH1A1NPSR1KDM4ELMNAGAA
SCHEMBL10638085 0.76 KDM4E (0.54) ALDH1A1NPSR1KDM4ELMNAGAA
SCHEMBL11368731 0.75 KDM4E (0.52) ALDH1A1NPSR1KDM4ELMNAGAA
SCHEMBL8434608 0.74 GAA (0.50) ALDH1A1NPSR1KDM4ELMNAGAA
SCHEMBL9668475 0.74 GAA (0.63) ALDH1A1NPSR1KDM4ELMNAGAA
SCHEMBL8433236 0.73 GAA (0.49) ALDH1A1NPSR1KDM4ELMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 260 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3365380-B1 VINYL CHLORIDE POLYMERS AND COMPOSITIONS FOR ADDITIVE MANUFACTURING AKDENIZ CHEMSON ADDITIVES AG (AT) 2023-04-26 EP disclosed
US-11542389-B2 Vinyl chloride polymers and compositions for additive manufacturing AKDENIZ CHEMSON ADDITIVES AG (AT) 2023-01-03 US disclosed
US-20210017374-A1 VINYL CHLORIDE POLYMERS AND COMPOSITIONS FOR ADDITIVE MANUFACTURING AKDENIZ CHEMSON ADDITIVES AG (AT) 2021-01-21 US disclosed
US-10829629-B2 Vinyl chloride polymers and compositions for additive manufacturing CHEMSON POLYMER-ADDITIVE AG (AT) 2020-11-10 US disclosed
WO-2020058337-A1 USE OF A MELAMINE BASED COMPOUND AND A HALS COMPOUND AS HEAT STABILIZER IN POLYMERS BOREALIS AG (AT) 2020-03-26 WO disclosed
EP-3626772-A1 USE OF A MELAMINE BASED COMPOUND AND A HALS COMPOUND AS HEAT STABILIZER IN POLYMERS Borealis AG (AT) 2020-03-25 EP disclosed
US-10365411-B2 Hardcoat film, polarizing plate, liquid crystal display, and method for manufacturing hardcoat film FUJIFILM CORPORATION (JP) 2019-07-30 US disclosed
US-20180305536-A1 VINYL CHLORIDE POLYMERS AND COMPOSITIONS FOR ADDITIVE MANUFACTURING AKDENIZ CHEMSON ADDITIVES AG (AT) 2018-10-25 US disclosed
EP-3365380-A1 VINYL CHLORIDE POLYMERS AND COMPOSITIONS FOR ADDITIVE MANUFACTURING Chemson Polymer-Additive AG (AT) 2018-08-29 EP disclosed
US-9951205-B2 Stable compositions of thiabendazole and iodine-containing fungicides LANXESS DEUTSCHLAND GMBH (DE) 2018-04-24 US disclosed
US-4331586-A MORPHOLINO-DIAMINOTRIAZINE OLIGOMERS AMERICAN CYANAMID COMPANY (US) 1982-05-25 US disclosed
US-4315848-A PROTECTIVE COATING FOR AUTOMOBILES CIBA-GEIGY CORPORATION (US) 1982-02-16 US disclosed
US-4314933-A 2,2,6,6-TETRAALKYLPIPERIDINE COMPOUNDS CIBA-GEIGY CORPORATION (US) 1982-02-09 US disclosed
EP-0006564-B1 2-(3.5-DISUBSTITUTED-2-HYDROXYPHENYL)-2H-BENZOTRIAZOLES AND STABILIZED COMPOSITIONS CONTAINING THEM CIBA-GEIGY AG (CH) 1981-12-30 EP disclosed
US-4278589-A 2-[2-Hydroxy-3,5-di-(α,α-dimethylbenzyl)phenyl]-2H-benzotriazole and stabilized compositions CIBA-GEIGY CORPORATION (US) 1981-07-14 US disclosed
US-4278590-A AUTOMOBILE FINISHES CIBA-GEIGY CORPORATION (US) 1981-07-14 US disclosed
EP-0016723-A1 Light stabilisation of two-layer composite lacquers CIBA-GEIGY AG (CH) 1980-10-01 EP disclosed
EP-0015230-A1 Stabilized organic Polymer comprising 2-(2-hydroxy-3,5-di-tert-octylphenyl)-2H-benzotriazole as a light-stabilizer CIBA-GEIGY AG (CH) 1980-09-03 EP disclosed
EP-0006564-A2 2-(3.5-disubstituted-2-hydroxyphenyl)-2H-benzotriazoles and stabilized compositions containing them CIBA-GEIGY AG (CH) 1980-01-09 EP disclosed
EP-0002753-A2 Stabilisation of heat-curable metallic enamel paints against the action of light, humidity and oxygen by the addition of polyalkylpiperidine derivatives CIBA-GEIGY AG (CH) 1979-07-11 EP disclosed