SCHEMBL6933598

SCHEMBL6933598

CC1(C)CC(NCc2ccccc2)CC(C)(C)N1O

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ACHE P22303 6/20 0.46
BACE1 P56817 6/20 0.46
BCHE P06276 4/20 0.46
FYN P06241 1/20 0.46
GRIN2B Q13224 2/20 0.46
OPRM1 P35372 2/20 0.46
OPRL1 P41146 2/20 0.46
CARM1 Q86X55 1/20 0.44
PRMT6 Q96LA8 1/20 0.44
KDM4E B2RXH2 3/20 0.44
GAA P10253 2/20 0.44
LMNA P02545 1/20 0.44
KMT2A Q03164 2/20 0.44
ALDH1A1 P00352 2/20 0.43
MEN1 O00255 1/20 0.42
RAB9A P51151 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
FABP6 P51161 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11161937 0.85 CARM1 (0.49) ACHEBACE1BCHEFYNGRIN2B
SCHEMBL6933594 0.84 KDM4E (0.48) ACHEBACE1BCHEFYNGRIN2B
SCHEMBL16683350 0.80 ALDH1A1 (0.40) KDM4EGAALMNAKMT2AALDH1A1
SCHEMBL536184 0.77 KDM4E (0.71) ACHEBACE1BCHEFYNGRIN2B
SCHEMBL9493508 0.76 ACHE (0.50) ACHEBACE1BCHECARM1PRMT6
SCHEMBL14632774 0.75 CCR3 (0.42) GAAKMT2AALDH1A1MEN1
SCHEMBL12037340 0.75 GRIN2B (0.50) ACHEBACE1BCHEFYNGRIN2B
SCHEMBL6933221 0.75 KMT2A (0.53) CARM1PRMT6KDM4EGAALMNA
SCHEMBL25537260 0.74 GRIN2B (0.46) ACHEBACE1BCHEFYNGRIN2B
SCHEMBL22411271 0.74 GRIN2B (0.53) ACHEBACE1BCHEFYNGRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6660181-B2 Inhibiting the premature polymerization of ethylenically unsaturated monomers by adding mixture comprising a first inhibitor comprising 4-amino-2,2,6,6-tetramethylpiperidinyloxy and other inhibitor CROMPTON CORPORATION 2003-12-09 US disclosed
US-20030080318-A1 Inhibition of polymerization of unsaturated monomers ADDIVANT USA, LLC 2003-05-01 US disclosed