Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 8/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.35 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6525379 | 0.88 | AR (0.58) | ARCYP19A1PIN1 | |
| SCHEMBL5358210 | 0.87 | AR (0.47) | ARCYP19A1PIN1 | |
| SCHEMBL14347623 | 0.75 | AR (0.42) | ARKIF11 | |
| SCHEMBL5358573 | 0.74 | AR (0.54) | ARKIF11 | |
| SCHEMBL5369671 | 0.73 | AR (0.60) | AR | |
| SCHEMBL5365095 | 0.71 | AR (0.65) | ARCYP19A1 | |
| SCHEMBL6466386 | 0.71 | AR (0.58) | ARCYP19A1 | |
| SCHEMBL6466161 | 0.65 | AR (0.58) | AR | |
| SCHEMBL5359676 | 0.64 | AR (0.53) | AR | |
| SCHEMBL5364107 | 0.64 | AR (0.56) | ARCYP19A1TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007145349-A2 | SUBSTITUTED PYRROLE DERIVATIVES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-12-21 | — | — | WO | disclosed |