Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 10/20 | 0.54 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | SLC2A1 | P11166 | 3/20 | 0.33 |
| ▸ | SLC2A3 | P11169 | 3/20 | 0.33 |
| ▸ | SLC2A4 | P14672 | 3/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | SLC2A2 | P11168 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.31 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.31 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.31 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.31 |
| ▸ | GABRP | O00591 | 1/20 | 0.31 |
| ▸ | GABRD | O14764 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5369671 | 0.79 | AR (0.60) | ARLMNAMAPTGRIA2GRIA4 | |
| SCHEMBL6525379 | 0.79 | AR (0.58) | ARGRIA2GRIA4 | |
| SCHEMBL5365095 | 0.79 | AR (0.65) | ARALDH1A1GRIA2GRIA4 | |
| SCHEMBL14347772 | 0.75 | AR (0.53) | ARPPARDCNR1KIF11 | |
| SCHEMBL6466386 | 0.75 | AR (0.58) | ARGRIA2GRIA4 | |
| SCHEMBL5362174 | 0.74 | AR (0.44) | ARKIF11 | |
| SCHEMBL6466161 | 0.73 | AR (0.58) | ARALDH1A1GRIA2GRIA4 | |
| SCHEMBL5362158 | 0.70 | AR (0.53) | ARSLC2A1SLC2A3SLC2A4CNR1 | |
| SCHEMBL5358210 | 0.70 | AR (0.47) | AR | |
| SCHEMBL24112327 | 0.69 | ALDH1A1 (0.34) | ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007145349-A2 | SUBSTITUTED PYRROLE DERIVATIVES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-12-21 | — | — | WO | disclosed |