SCHEMBL536227

SCHEMBL536227

O=C(OCc1ccccc1)C(O)c1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.55
MAPK1 P28482 2/20 0.53
TDP1 Q9NUW8 2/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
SLC6A2 P23975 1/20 0.53
SLC6A3 Q01959 1/20 0.53
KMT2A Q03164 1/20 0.53
LMNA P02545 5/20 0.52
LTA4H P09960 1/20 0.50
LAP3 P28838 1/20 0.50
HCAR2 Q8TDS4 1/20 0.49
CES2 O00748 1/20 0.47
CES1 P23141 1/20 0.47
ATM Q13315 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5117818 1.00 ALDH1A1 (0.55) ALDH1A1MAPK1TDP1L3MBTL1SLC6A2
SCHEMBL2231648 1.00 ALDH1A1 (0.55) ALDH1A1MAPK1TDP1L3MBTL1SLC6A2
SCHEMBL10727982 0.91 LMNA (0.57) ALDH1A1MAPK1TDP1L3MBTL1SLC6A2
SCHEMBL10727978 0.91 LMNA (0.57) ALDH1A1MAPK1TDP1L3MBTL1SLC6A2
SCHEMBL11182822 0.88 L3MBTL1 (0.50) ALDH1A1MAPK1TDP1L3MBTL1SLC6A2
SCHEMBL3736834 0.85 ATM (0.65) ALDH1A1TDP1LTA4HLAP3ATM
SCHEMBL22615678 0.85 ATM (0.65) ALDH1A1TDP1LTA4HLAP3ATM
SCHEMBL11845149 0.84 L3MBTL1 (0.46) ALDH1A1MAPK1TDP1L3MBTL1SLC6A2
SCHEMBL8792364 0.84 PTGS1 (0.52) ALDH1A1SLC6A2LMNALTA4HLAP3
Mandelic Acid, Methyl Ester SCHEMBL7704691 0.83 ALDH1A1 (0.50) ALDH1A1MAPK1TDP1L3MBTL1SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 182 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118702633-A Preparation method of drug chlorinated intermediate for preventing cytomegalovirus infection 台州职业技术学院 2024-09-27 CN claimed
CN-118218027-A Application of polydentate ligand/ruthenium catalyst and method for preparing diol compound by hydrogenation reaction of alpha-hydroxy ester 郑州大学 2024-06-21 CN claimed
JP-59098033-A None JP disclosed
JP-57210889-A None JP disclosed
US-20250388534-A1 SUPRAMOLECULAR TRANEXAMIC ACID-MANDELIC ACID IONIC SALT AS WELL AS PREPARATION METHOD THEREFOR AND USE THEREOF SHENZHEN SHINEHIGH INNOVATION CO., LTD. (CN) 2025-12-25 US disclosed
CN-119930682-A Novel method for synthesizing rosuvastatin intermediate side chain 江苏阿尔法集团福瑞药业(宿迁)有限公司 2025-05-06 CN disclosed
CN-115403761-B Multi-glycol modified lipid compound and preparation method and application thereof 天津键凯科技有限公司 2025-04-25 CN disclosed
CN-118843629-A Antiviral compounds and methods of making and using the same 吉利德科学公司 2024-10-25 CN disclosed
CN-118702633-A Preparation method of drug chlorinated intermediate for preventing cytomegalovirus infection 台州职业技术学院 2024-09-27 CN disclosed
CN-114410699-B Method for producing R-mandelic acid by biocatalysis 安徽泰格生物科技有限公司 2024-08-16 CN disclosed
CN-118488948-A IKAROS zinc finger family degradation agent and application thereof 吉利德科学公司 2024-08-13 CN disclosed
CN-1265096-A Hydrazine derivatives HOFFMANN LA ROCHE (CH) 2000-08-30 CN disclosed
EP-0993442-A1 HYDRAZINE DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 2000-04-19 EP disclosed
WO-1999001428-A1 HYDRAZINE DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 1999-01-14 WO disclosed
EP-0554455-A1 OPTICALLY ACTIVE INTERMEDIATE AND PRODUCTION THEREOF SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) 1993-08-11 EP disclosed
EP-0152083-B1 PROCESS FOR PRODUCING POWDER OF MICROCAPSULES KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1989-05-03 EP disclosed
US-4601863-A Process for producing powder of microcapsules KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1986-07-22 US disclosed
EP-0152083-A2 Process for producing powder of microcapsules KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1985-08-21 EP disclosed
JP-S5998033-A PREPARATION OF MANDELIC ACID NIPPON SYNTHETIC CHEM IND CO LTD:THE 1984-06-06 JP disclosed
JP-S57210889-A HEAT-SENSITIVE RECORDING PAPER HONSHU PAPER CO LTD 1982-12-24 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250388534-A1 SUPRAMOLECULAR TRANEXAMIC ACID-MANDELIC ACID IONIC SALT AS WELL AS PREPARATION METHOD THEREFOR AND USE THEREOF F7, F8, SLC7A1 ALDH1A1 1207/4885MAPK1 1330/4885TDP1 1438/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.