Sugi Predict

Sugi Predict / Compounds / SCHEMBL5362363

SCHEMBL5362363

SCHEMBL5362363

c1ccc(-c2ccc3cnncc3c2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ESR1 P03372 4/20 0.52
▸ ESR2 Q92731 4/20 0.52
▸ CLK4 Q9HAZ1 2/20 0.50
▸ BACE1 P56817 1/20 0.50
▸ FGFR1 P11362 1/20 0.50
▸ DYRK3 O43781 1/20 0.50
▸ CLK1 P49759 1/20 0.50
▸ CLK2 P49760 1/20 0.50
▸ CLK3 P49761 1/20 0.50
▸ GSK3B P49841 1/20 0.50
▸ CDK5 Q00535 1/20 0.50
▸ DYRK1A Q13627 1/20 0.50
▸ CDK5R1 Q15078 1/20 0.50
▸ DYRK2 Q92630 1/20 0.50
▸ DYRK1B Q9Y463 1/20 0.50
▸ CYP11B1 P15538 2/20 0.47
▸ CYP11B2 P19099 2/20 0.47
▸ CYP17A1 P05093 1/20 0.47
▸ CYP19A1 P11511 1/20 0.47
▸ MAP4K4 O95819 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL27523644 0.83 ALDH1A1 (0.53) FGFR1CYP19A1NPC1GABRA1GABRG2
SCHEMBL29677310 0.80 PGR (0.46) ESR1ESR2CYP11B1CYP11B2MAP4K4
SCHEMBL30304006 0.80 ESR1 (0.73) ESR1ESR2CLK4BACE1FGFR1
SCHEMBL16107069 0.80 ESR1 (0.73) ESR1ESR2CLK4BACE1FGFR1
SCHEMBL27511439 0.78 ESR1 (0.74) ESR1ESR2CLK4BACE1FGFR1
SCHEMBL5007325 0.77 PRKCZ (0.70) ESR1ESR2BACE1FGFR1CYP11B1
SCHEMBL6355545 0.77 CYP11B2 (0.61) ESR1ESR2CYP11B1CYP11B2CYP17A1
SCHEMBL24965958 0.77 PIK3CD (0.61) ESR2CLK4MAP4K4NPC1
SCHEMBL28485227 0.76 BACE1 (0.44) BACE1FGFR1CYP11B1GABRA1GABRG2
Biphenyl SCHEMBL4007823 0.75 ESR1 (0.70) ESR1ESR2BACE1CYP11B1CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109476596-A Organic electronic element compound, organic electronic element and its electronic device using the compound 德山新勒克斯有限公司 2019-03-15 — — CN disclosed
CN-101421257-A Agents that disrupt cellular replication and their use in inhibiting pathological conditions EUROPEAN MOLECULAR BIOLOGY LAB EMBL (DE) 2009-04-29 — — CN disclosed
US-7335466-B2 Silver salt photothermographic dry imaging material, image recording method and image forming method for the same KONICA MINOLTA HOLDINGS, INC. (JP) 2008-02-26 — — US disclosed
US-7335466-B2 Silver salt photothermographic dry imaging material, image recording method and image forming method for the same KONICA MINOLTA HOLDINGS, INC. (JP) 2008-02-26 — — US disclosed
US-7229753-B2 Photothermographic material and method for forming images FUJIFILM CORPORATION (JP) 2007-06-12 — — US disclosed
US-7229753-B2 Photothermographic material and method for forming images FUJIFILM CORPORATION (JP) 2007-06-12 — — US disclosed
US-7202019-B2 Photothermographic imaging material KONICA MINOLTA HOLDINGS, INC. (JP) 2007-04-10 — — US disclosed
US-20070003882-A9 Photothermographic material, and image forming method using same FUKUI KOUTA 2007-01-04 — — US disclosed
US-20070003882-A9 Photothermographic material, and image forming method using same FUKUI KOUTA 2007-01-04 — — US disclosed
US-7115359-B2 Photothermographic material KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2006-10-03 — — US disclosed
US-20050037298-A1 Photothermographic material KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2005-02-17 — — US disclosed
EP-1500973-A2 Photothermographic material Konica Minolta Medical & Graphic, Inc. (JP) 2005-01-26 — — EP disclosed
US-20040101794-A1 Photothermographic imaging material KONICA MINOLTA HOLDINGS, INC. (JP) 2004-05-27 — — US disclosed