Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ2 | O43526 | 1/20 | 0.46 |
| ▸ | LDHA | P00338 | 1/20 | 0.45 |
| ▸ | LDHB | P07195 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5362651 | 1.00 | KCNQ2 (0.46) | KCNQ2LDHALDHBTP53SMN1; SMN2 | |
| SCHEMBL20826432 | 0.78 | L3MBTL1 (0.54) | SMN1; SMN2ALDH1A1KMT2ATDP1L3MBTL1 | |
| SCHEMBL10388122 | 0.78 | ESR1 (0.64) | KMT2AL3MBTL1ESR1ESR2 | |
| SCHEMBL27610226 | 0.78 | ESR1 (0.47) | HPGDMAPTALDH1A1NPSR1KMT2A | |
| SCHEMBL5372320 | 0.78 | KCNQ2 (0.43) | KCNQ2ALDH1A1KMT2AMEN1GAA | |
| SCHEMBL5372317 | 0.78 | KCNQ2 (0.43) | KCNQ2ALDH1A1KMT2AMEN1GAA | |
| SCHEMBL6784455 | 0.77 | HIF1A (0.54) | TP53SMN1; SMN2HPGDMAPTALDH1A1 | |
| SCHEMBL631468 | 0.77 | ESR1 (0.46) | LDHALDHBMAPTALDH1A1KMT2A | |
| SCHEMBL20826234 | 0.77 | L3MBTL1 (0.57) | LDHALDHBCNR2KMT2AL3MBTL1 | |
| SCHEMBL3168058 | 0.76 | KMT2A (0.59) | ALDH1A1KMT2AMEN1GAACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7173139-B2 | Enantioselective 1,4-addition of aromatic nucleophiles to α,β-unsaturated aldehydes using chiral organic catalysts | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2007-02-06 | — | — | US | disclosed |
| US-7173139-B2 | Enantioselective 1,4-addition of aromatic nucleophiles to α,β-unsaturated aldehydes using chiral organic catalysts | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2007-02-06 | — | — | US | disclosed |
| US-7173139-B2 | Enantioselective 1,4-addition of aromatic nucleophiles to α,β-unsaturated aldehydes using chiral organic catalysts | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2007-02-06 | — | — | US | disclosed |
| EP-1412335-A4 | ENANTIOSELECTIVE TRANSFORMATION OF $g(a), $g(b)-UNSATURATED ALDEHYDES USING CHIRAL ORGANIC CATALYSTS | CALIFORNIA INST OF TECHN (US) | 2004-11-17 | — | — | EP | disclosed |
| US-6784323-B2 | Enantioselective transformation of α,β-unsaturated aldehydes using chiral organic catalysts | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2004-08-31 | — | — | US | disclosed |
| EP-1412335-A2 | ENANTIOSELECTIVE TRANSFORMATION OF $g(a), $g(b)-UNSATURATED ALDEHYDES USING CHIRAL ORGANIC CATALYSTS | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2004-04-28 | — | — | EP | disclosed |
| US-20030236438-A1 | Enantioselective 1,4-addition of aromatic nucleophiles to alpha,beta-unsaturated aldehydes using chiral organic catalysts | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2003-12-25 | — | — | US | disclosed |
| US-20030109718-A1 | Enantioselective transformation of alpha, beta-unsaturated aldehydes using chiral organic catalysts | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2003-06-12 | — | — | US | disclosed |
| WO-2003002491-A2 | ENANTIOSELECTIVE TRANSFORMATION OF α, β-UNSATURATED ALDEHYDES USING CHIRAL ORGANIC CATALYSTS | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2003-01-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030109718-A1 | Enantioselective transformation of alpha, beta-unsaturated aldehydes using chiral organic catalysts | ALDH1A1, GAR1, ALDH1B1 | KCNQ2 3108/4885LDHA 1819/4885LDHB 2322/4885 |
| US-20030236438-A1 | Enantioselective 1,4-addition of aromatic nucleophiles to alpha,beta-unsaturated aldehydes using chiral organic catalysts | NAT1, AOX1, ALDH7A1 | KCNQ2 4401/4885LDHA 1357/4885LDHB 1973/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.