SCHEMBL5363097

SCHEMBL5363097

CCC(C)(C)OC(=O)C1CCC(C(=O)OC(C)(C)CC)CC1

nearest known ligand 0.36

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 1/20 0.36
ALDH1A1 P00352 4/20 0.35
TSHR P16473 2/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
MAPT P10636 3/20 0.33
TDP1 Q9NUW8 1/20 0.33
ADRB2 P07550 1/20 0.33
ADRB1 P08588 1/20 0.33
ADRB3 P13945 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
THRA P10827 1/20 0.32
THRB P10828 1/20 0.32
GAA P10253 1/20 0.32
HSD11B1 P28845 1/20 0.32
RECQL P46063 1/20 0.31
ATM Q13315 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15000259 0.92 HRH3 (0.33) HRH3ALDH1A1TSHRMEN1KMT2A
SCHEMBL5722404 0.92 ADRB2 (0.41) HRH3ALDH1A1TSHRMEN1KMT2A
SCHEMBL24696275 0.91 MAPT (0.46) ALDH1A1TSHRMEN1KMT2AMAPT
SCHEMBL1130166 0.90 ALDH1A1 (0.42) ALDH1A1MEN1KMT2AADRB2ADRB1
SCHEMBL28056841 0.87 TSHR (0.41) HRH3ALDH1A1TSHRMEN1KMT2A
SCHEMBL15160792 0.85 HRH3 (0.40) HRH3ALDH1A1TSHRMEN1KMT2A
SCHEMBL5368876 0.84 BTK (0.38) ALDH1A1MEN1KMT2AMAPTTDP1
SCHEMBL17404444 0.83 FKBP1A (0.32) ALDH1A1TSHRMEN1KMT2A
SCHEMBL24129388 0.82 HRH3 (0.36) HRH3ALDH1A1TSHRMEN1KMT2A
SCHEMBL15159129 0.81 HRH3 (0.57) HRH3ALDH1A1TSHRMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7208545-B1 Selected cyclohexane -1,3-and -1,4-dicarboxylic acid esters BASF AKTIENGESELLSCHAFT (DE) 2007-04-24 US claimed
EP-1194396-B1 SELECTED CYCLOHEXANE-1,3- AND 1,4-DICARBOXYLIC ACID ESTERS BASF AG (DE) 2005-11-09 EP claimed
US-7208545-B1 Selected cyclohexane -1,3-and -1,4-dicarboxylic acid esters BASF AKTIENGESELLSCHAFT (DE) 2007-04-24 US disclosed