Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | FKBP1A | P62942 | 5/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 2/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16377766 | 0.90 | BTK (0.35) | BTKSMN1; SMN2HSD17B10ADRB2ADRB1 | |
| SCHEMBL5722404 | 0.89 | ADRB2 (0.41) | BTKSMN1; SMN2HSD17B10ADRB2ADRB1 | |
| SCHEMBL1130166 | 0.87 | ALDH1A1 (0.42) | SMN1; SMN2HSD17B10ADRB2ADRB1ADRB3 | |
| SCHEMBL5371328 | 0.85 | BTK (0.38) | BTKSMN1; SMN2HSD17B10ADRB2ADRB1 | |
| SCHEMBL5363097 | 0.84 | HRH3 (0.36) | SMN1; SMN2ADRB2ADRB1ADRB3KMT2A | |
| SCHEMBL24129388 | 0.83 | HRH3 (0.36) | BTKKMT2ATDP1MEN1ALDH1A1 | |
| SCHEMBL5368763 | 0.83 | BTK (0.36) | BTKSMN1; SMN2HSD17B10ADRB2ADRB1 | |
| SCHEMBL14883986 | 0.82 | BTK (0.31) | BTKFKBP1A | |
| SCHEMBL12968052 | 0.82 | L3MBTL1 (0.31) | SMN1; SMN2HSD17B10ADRB2ADRB1ADRB3 | |
| SCHEMBL25762342 | 0.80 | BTK (0.50) | BTKSMN1; SMN2HSD17B10ADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1194396-B1 | SELECTED CYCLOHEXANE-1,3- AND 1,4-DICARBOXYLIC ACID ESTERS | BASF AG (DE) | 2005-11-09 | — | — | EP | claimed |
| US-7208545-B1 | Selected cyclohexane -1,3-and -1,4-dicarboxylic acid esters | BASF AKTIENGESELLSCHAFT (DE) | 2007-04-24 | — | — | US | disclosed |