Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.61 |
| ▸ | CTSB | P07858 | 5/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | AR | P10275 | 1/20 | 0.50 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CASP6 | P55212 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.42 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29662561 | 1.00 | TDP1 (0.61) | TDP1CTSBALDH1A1ARVCAM1 | |
| SCHEMBL1126793 | 0.88 | TDP1 (0.75) | TDP1CTSBALDH1A1VCAM1ATM | |
| SCHEMBL7788656 | 0.87 | TDP1 (0.80) | TDP1CTSBALDH1A1ARHPRT1 | |
| SCHEMBL57166 | 0.77 | TDP1 (1.00) | TDP1CTSBALDH1A1CYP3A4ALOX15 | |
| SCHEMBL29475175 | 0.77 | TDP1 (1.00) | TDP1CTSBALDH1A1CYP3A4ALOX15 | |
| SCHEMBL26059132 | 0.76 | TDP1 (0.62) | TDP1CTSBALDH1A1VCAM1HIF1A | |
| SCHEMBL26059133 | 0.76 | TDP1 (0.62) | TDP1CTSBALDH1A1VCAM1HIF1A | |
| SCHEMBL1351778 | 0.76 | MAPT (0.56) | TDP1CTSBALDH1A1VCAM1ATM | |
| SCHEMBL3606794 | 0.75 | TDP1 (0.61) | TDP1CTSBALDH1A1ARHPRT1 | |
| SCHEMBL8722948 | 0.75 | TDP1 (0.61) | TDP1CTSBALDH1A1ARHPRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 252 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116925498-A | High-pressure-bearing branched epoxy resin plugging material and oil-based drilling fluid | 西南石油大学 | 2023-10-24 | — | — | CN | claimed |
| CN-115232010-A | Method for preparing 1-fluoro-4-nitronaphthalene through microchannel reaction | 中国科学技术大学先进技术研究院 | 2022-10-25 | — | — | CN | claimed |
| EP-1976495-A2 | COMPOUNDS ACTING ON THE SEROTONIN TRANSPORTER | Aarhus Universitet (DK) | 2008-10-08 | — | — | EP | claimed |
| CN-100410256-C | Optical diamine monomer containing di-dehydrated-hexitol unit and process for preparing same | UNIV TSINGHUA (CN) | 2008-08-13 | — | — | CN | claimed |
| WO-2007076875-A2 | COMPOUNDS ACTING ON THE SEROTONIN TRANSPORTER | AARHUS UNIVERSITET (DK) | 2007-07-12 | — | — | WO | claimed |
| CN-1320031-C | Polyamide containing isosorbide unit and process for preparing same | UNIV TSINGHUA (CN) | 2007-06-06 | — | — | CN | claimed |
| CN-1702071-A | Optical diamine monomer containing di-dehydrated-hexitol unit and process for preparing same | UNIV TSINGHUA (CN) | 2005-11-30 | — | — | CN | claimed |
| CN-1702095-A | Polyamide containing isosorbide unit and process for preparing same | UNIV TSINGHUA (CN) | 2005-11-30 | — | — | CN | claimed |
| CN-1702097-A | Optical polyimide containing isosorbide unit and process for preparing same | UNIV TSINGHUA (CN) | 2005-11-30 | — | — | CN | claimed |
| CN-116354891-B | Naphthyl phenyl ether compound, and preparation method and application thereof | 河南省锐达医药科技有限公司 | 2025-01-07 | — | — | CN | disclosed |
| EP-3558969-B1 | PYRAZOLE DERIVATIVES AS MALT1 INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2024-09-18 | — | — | EP | disclosed |
| US-12077521-B2 | Pyrazole derivatives as MALT1 inhibitors | JANSSEN PHARMACEUTICA NV (BE) | 2024-09-03 | — | — | US | disclosed |
| WO-2024141052-A1 | ESTROGEN-RECEPTOR MODULATOR AND USE THEREOF | 江苏威凯尔医药科技有限公司 | 2024-07-04 | — | — | WO | disclosed |
| CN-118271284-A | Estrogen receptor modulators and uses thereof | 江苏威凯尔医药科技有限公司 | 2024-07-02 | — | — | CN | disclosed |
| US-4423126-A | FORMING NAPHTHOQUINONEIMIDE DYE | EASTMAN KODAK COMPANY (US) | 1983-12-27 | — | — | US | disclosed |
| EP-0095899-A2 | Color-forming carboxamidonaphthalene dye precursor compounds, photographic materials containing them and corresponding carboximide dyes | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1983-12-07 | — | — | EP | disclosed |
| US-4200588-A | ANTILIPEMIC AGENTS, ANTIATHEROSCLEROTIC | THE UPJOHN COMPANY (US) | 1980-04-29 | — | — | US | disclosed |
| US-4130561-A | Polycycloanilines | THE UPJOHN COMPANY (US) | 1978-12-19 | — | — | US | disclosed |
| US-4120899-A | HYPOLIPEDEMIC, ANTIATHEROSCLEROTIC | THE UPJOHN COMPANY (US) | 1978-10-17 | — | — | US | disclosed |
| US-4036977-A | HYPOLIPEDEMIC AND ANTIATHEROSCLEROTIC PROPERTIES | THE UPJOHN COMPANY (US) | 1977-07-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12077521-B2 | Pyrazole derivatives as MALT1 inhibitors | MALT1, PPP3R1, SQSTM1 | TDP1 428/4885CTSB 1195/4885ALDH1A1 2543/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.