Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 6/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8222493 | 0.86 | RXFP1 (0.40) | ROCK2KMT2ATP53RXFP1ALDH1A1 | |
| SCHEMBL5353056 | 0.84 | SLC6A9 (0.42) | ROCK2SLC6A9CYP2D6CYP2C19SLC6A5 | |
| SCHEMBL5414112 | 0.79 | SLC6A9 (0.42) | ROCK2SLC6A9CYP2D6CYP2C19SLC6A5 | |
| SCHEMBL3905209 | 0.77 | LMNA (0.36) | KMT2AALDH1A1GAALMNAMEN1 | |
| SCHEMBL3903948 | 0.76 | SLC6A9 (0.48) | SLC6A9 | |
| SCHEMBL8233755 | 0.76 | SLC6A9 (0.44) | ROCK2SLC6A9CYP2D6CYP2C19SLC6A5 | |
| Hydrochloric Acid SCHEMBL3910216 | 0.76 | SLC6A9 (0.48) | SLC6A9 | |
| SCHEMBL3903986 | 0.76 | KMT2A (0.51) | KMT2AALDH1A1HPGDGAALMNA | |
| SCHEMBL3901142 | 0.75 | KMT2A (0.42) | KMT2ATP53RXFP1ALDH1A1HPGD | |
| SCHEMBL3905138 | 0.75 | ATM (0.44) | SLC6A9KMT2ARXFP1POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007147834-A1 | GLYCINE TRANSPORTER INHIBITING COMPOUNDS AND USES IN MEDICINE | GLAXO GROUP LIMITED (GB) | 2007-12-27 | — | — | WO | claimed |
| WO-2007147834-A1 | GLYCINE TRANSPORTER INHIBITING COMPOUNDS AND USES IN MEDICINE | GLAXO GROUP LIMITED (GB) | 2007-12-27 | — | — | WO | disclosed |