Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 14/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5414112 | 0.89 | SLC6A9 (0.42) | SLC6A9CYP2D6CYP2C19SLC6A5ROCK2 | |
| SCHEMBL8231582 | 0.87 | SLC6A9 (0.43) | SLC6A9SLC6A5ROCK2KMT2ATP53 | |
| SCHEMBL1350280 | 0.85 | SLC6A9 (0.45) | SLC6A9CYP2D6CYP2C19SLC6A5ROCK2 | |
| SCHEMBL1348705 | 0.84 | SLC6A9 (0.44) | SLC6A9CYP2D6CYP2C19SLC6A5ROCK2 | |
| SCHEMBL1349517 | 0.81 | SLC6A9 (0.42) | SLC6A9CYP2D6CYP2C19SLC6A5ROCK2 | |
| SCHEMBL3262198 | 0.77 | SLC6A9 (0.49) | SLC6A9CYP2D6CYP2C19SLC6A5 | |
| SCHEMBL5353056 | 0.76 | SLC6A9 (0.42) | SLC6A9CYP2D6CYP2C19SLC6A5ROCK2 | |
| SCHEMBL5363493 | 0.76 | ROCK2 (0.38) | SLC6A9CYP2D6CYP2C19SLC6A5ROCK2 | |
| SCHEMBL3243558 | 0.76 | ROCK2 (0.44) | SLC6A9SLC6A5ROCK2KMT2ATP53 | |
| SCHEMBL1348087 | 0.75 | SLC6A9 (0.54) | SLC6A9CYP2D6CYP2C19SLC6A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007147834-A1 | GLYCINE TRANSPORTER INHIBITING COMPOUNDS AND USES IN MEDICINE | GLAXO GROUP LIMITED (GB) | 2007-12-27 | — | — | WO | disclosed |