Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.51 |
| ▸ | TP53 | P04637 | 6/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.36 |
| ▸ | NPC1 | O15118 | 5/20 | 0.36 |
| ▸ | RAB9A | P51151 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2996722 | 0.83 | TP53 (0.71) | MAPTTP53GAAF2RL3SMN1; SMN2 | |
| SCHEMBL5300838 | 0.82 | TP53 (0.62) | MAPTTP53GAAF2RL3SMN1; SMN2 | |
| SCHEMBL5371749 | 0.75 | ALDH1A3 (0.40) | MAPTTP53GAASMN1; SMN2NPC1 | |
| SCHEMBL5365310 | 0.74 | LRRK2 (0.35) | MAPTTP53GAAF2RL3SMN1; SMN2 | |
| SCHEMBL5363986 | 0.71 | ALDH1A1 (0.39) | MAPTSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL20337636 | 0.68 | NPC1 (0.39) | MAPTTP53GAASMN1; SMN2NPC1 | |
| SCHEMBL5364794 | 0.67 | NPC1 (0.51) | MAPTTP53GAASMN1; SMN2NPC1 | |
| SCHEMBL5368687 | 0.66 | KDM4E (0.33) | MAPTTP53GAAF2RL3SMN1; SMN2 | |
| SCHEMBL5375882 | 0.66 | NPC1 (0.41) | SMN1; SMN2NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL19618901 | 0.65 | ESR2 (0.43) | NPC1RAB9AALDH1A1ARMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007034282-A2 | DIARYL-IMIDAZOLE COMPOUNDS CONDENSED WITH A HETEROCYCLE AS C3A RECEPTOR ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2007-03-29 | — | — | WO | disclosed |