Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.58 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.58 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7956581 | 0.92 | MAPT (0.62) | MAPTHSP90AA1HTTNPSR1MEN1 | |
| Benzene SCHEMBL28006415 | 0.90 | MAPT (0.60) | MAPTHSP90AA1HTTNPSR1MEN1 | |
| SCHEMBL6770205 | 0.90 | MAPT (0.68) | MAPTHSP90AA1HTTNPSR1MEN1 | |
| SCHEMBL31406534 | 0.89 | LMNA (0.70) | MAPTHSP90AA1HTTNPSR1MEN1 | |
| SCHEMBL14438107 | 0.89 | LMNA (0.70) | MAPTHSP90AA1HTTNPSR1MEN1 | |
| SCHEMBL28527221 | 0.89 | LMNA (0.70) | MAPTHSP90AA1HTTNPSR1MEN1 | |
| SCHEMBL9305910 | 0.89 | LMNA (0.70) | MAPTHSP90AA1HTTNPSR1MEN1 | |
| SCHEMBL22439001 | 0.89 | LMNA (0.70) | MAPTHSP90AA1HTTNPSR1MEN1 | |
| SCHEMBL22324528 | 0.89 | LMNA (0.70) | MAPTHSP90AA1HTTNPSR1MEN1 | |
| SCHEMBL9309481 | 0.89 | LMNA (0.70) | MAPTHSP90AA1HTTNPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109096420-B | Catalyst for olefin polymerization and olefin polymerization method | 中国石油化工股份有限公司 | 2021-05-11 | — | — | CN | claimed |
| US-8998518-B2 | Dual cleaning apparatus | MUHR-SWEENEY AUDREY (US) | 2015-04-07 | — | — | US | claimed |
| US-20130327357-A1 | DUAL CLEANING APPARATUS | MUHR-SWEENEY AUDREY (US) | 2013-12-12 | — | — | US | claimed |
| US-8534945-B2 | Dual cleaning apparatus | MUHR-SWEENEY AUDREY (US) | 2013-09-17 | — | — | US | claimed |
| US-20120207530-A1 | DUAL CLEANING APPARATUS | MUHR-SWEENEY AUDREY (US) | 2012-08-16 | — | — | US | claimed |
| US-7553100-B2 | Dual cleaning apparatus | MUHR-SWEENEY AUDREY | 2009-06-30 | — | — | US | claimed |
| US-20050147455-A1 | Dual cleaning apparatus | MUHR-SWEENEY AUDREY (US) | 2005-07-07 | — | — | US | claimed |
| US-20040136770-A1 | Dual cleaning apparatus | MUHR-SWEENEY AUDREY (US) | 2004-07-15 | — | — | US | claimed |
| EP-3782995-B1 | SPIRO CONDENSED IMIDAZOLINE-2,4-DIONE DERIVATIVES AS HISTONE ACETYLTRANSFERASE INHIBITORS FOR THE TREATMENT OF CANCER DISEASES | SHANGHAI INST MATERIA MEDICA CAS (CN) | 2023-11-22 | — | — | EP | disclosed |
| CN-109096420-B | Catalyst for olefin polymerization and olefin polymerization method | 中国石油化工股份有限公司 | 2021-05-11 | — | — | CN | disclosed |
| US-10654837-B2 | Sulphamoylaryl derivatives and use thereof as medicaments for the treatment of liver fibrosis | JANSSEN PHARMACEUTICA NV (BE) | 2020-05-19 | — | — | US | disclosed |
| US-10654837-B2 | Sulphamoylaryl derivatives and use thereof as medicaments for the treatment of liver fibrosis | JANSSEN PHARMACEUTICA NV (BE) | 2020-05-19 | — | — | US | disclosed |
| US-20190345145-A1 | SULPHAMOYLARYL DERIVATIVES AND USE THEREOF AS MEDICAMENTS FOR THE TREATMENT OF LIVER FIBROSIS | JOHNSON & JOHNSON (CHINA) INVESTMENT LTD. (CN) | 2019-11-14 | — | — | US | disclosed |
| US-20190345145-A1 | SULPHAMOYLARYL DERIVATIVES AND USE THEREOF AS MEDICAMENTS FOR THE TREATMENT OF LIVER FIBROSIS | JOHNSON & JOHNSON (CHINA) INVESTMENT LTD. (CN) | 2019-11-14 | — | — | US | disclosed |
| WO-2003018019-A2 | NEW USE OF CYCLIC COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-03-06 | — | — | WO | disclosed |
| EP-1259499-A1 | THIAZEPINYL HYDROXAMIC ACID DERIVATIVES AS MATRIX METALLOPROTEINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-27 | — | — | EP | disclosed |
| WO-2001060808-A1 | THIAZEPINYL HYDROXAMIC ACID DERIVATIVES AS MATRIX METALLOPROTEINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-08-23 | — | — | WO | disclosed |
| US-6245779-B1 | ANALGESICS; ANTIINFLAMMATORY AGENTS | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2001-06-12 | — | — | US | disclosed |
| EP-0997463-A1 | NAPHTHYRIDINE DERIVATIVES | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2000-05-03 | — | — | EP | disclosed |
| US-6030630-A | Cosmetic compositions for the hair or skin based on sulfone copolyesters with polyorganosiloxane units | RHODIA CHIMIE (FR) | 2000-02-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10654837-B2 | Sulphamoylaryl derivatives and use thereof as medicaments for the treatment of liver fibrosis | HTR2B, HTR3B, HTR1A | MAPT 4615/4885HSP90AA1 743/4885HTT 2782/4885 |
| US-20190345145-A1 | SULPHAMOYLARYL DERIVATIVES AND USE THEREOF AS MEDICAMENTS FOR THE TREATMENT OF LIVER FIBROSIS | HTR2B, HTR3B, HTR1A | MAPT 4615/4885HSP90AA1 743/4885HTT 2782/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.