Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.35 |
| ▸ | MPO | P05164 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL535957 | 0.86 | CYP1A2 (0.33) | CYP1A2CYP2C9 | |
| SCHEMBL536006 | 0.78 | — | — | |
| SCHEMBL1665906 | 0.77 | PNP (0.31) | MPO | |
| SCHEMBL7597747 | 0.75 | MPO (0.38) | SLC6A4MPO | |
| SCHEMBL7607407 | 0.73 | MPO (0.40) | SLC6A4MPO | |
| SCHEMBL20165 | 0.73 | DHFR (0.33) | — | |
| SCHEMBL20744797 | 0.73 | — | — | |
| SCHEMBL7602254 | 0.72 | MPO (0.40) | SLC6A4MPO | |
| SCHEMBL26506 | 0.72 | SUMO1 (0.36) | — | |
| SCHEMBL2938692 | 0.72 | PNP (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2414527-B1 | CONVERSION OF ALPHA-HYDROXYALKYLATED RESIDUES IN BIOMOLECULES USING METHYLTRANSFERASES | BIOTECHNOLOGIJOS INST (LT) | 2015-05-20 | — | — | EP | disclosed |
| EP-2414528-B1 | DERIVATIZATION OF BIOMOLECULES BY COVALENT COUPLING OF NON-COFACTOR COMPOUNDS USING METHYLTRANSFERASES | UNIV VILNIUS (LT) | 2014-05-07 | — | — | EP | disclosed |
| EP-2414528-A1 | DERIVATIZATION OF BIOMOLECULES BY COVALENT COUPLING OF NON-COFACTOR COMPOUNDS USING METHYLTRANSFERASES | Biotechnologijos Institutas (LT) | 2012-02-08 | — | — | EP | disclosed |
| EP-2414527-A1 | CONVERSION OF ALPHA-HYDROXYALKYLATED RESIDUES IN BIOMOLECULES USING METHYLTRANSFERASES | Biotechnologijos Institutas (LT) | 2012-02-08 | — | — | EP | disclosed |
| WO-2010115847-A1 | CONVERSION OF ALPHA-HYDROXYALKYLATED RESIDUES IN BIOMOLECULES USING METHYLTRANSFERASES | BIOTECHNOLOGIJOS INSTITUTAS (LT) | 2010-10-14 | — | — | WO | disclosed |
| WO-2010115846-A1 | DERIVATIZATION OF BIOMOLECULES BY COVALENT COUPLING OF NON-COFACTOR COMPOUNDS USING METHYLTRANSFERASES | BIOTECHNOLOGIJOS INSTITUTAS (LT) | 2010-10-14 | — | — | WO | disclosed |