Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ADK | P55263 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13203111 | 0.97 | XDH (0.47) | XDHLMNAALOX15KDM4EHPGD | |
| SCHEMBL12787092 | 0.97 | XDH (0.47) | XDHLMNAALOX15KDM4EHPGD | |
| SCHEMBL13203113 | 0.95 | XDH (0.46) | XDHLMNAALOX15KDM4EHPGD | |
| SCHEMBL23511349 | 0.89 | ADK (0.50) | XDHLMNAKDM4EHPGDALDH1A1 | |
| SCHEMBL23511398 | 0.89 | LMNA (0.49) | XDHLMNAKDM4EHPGDALDH1A1 | |
| SCHEMBL9937001 | 0.89 | NOTUM (0.58) | SMN1; SMN2ADORA2AADORA1RAB9A | |
| SCHEMBL25069371 | 0.87 | ADK (0.49) | XDHLMNAKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL23511350 | 0.87 | ALDH1A1 (0.56) | XDHKDM4ESMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL25069217 | 0.87 | ADK (0.49) | XDHLMNAKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL25069214 | 0.87 | ADK (0.49) | XDHLMNAKDM4EHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7271266-B2 | Substituted 2,3-diphenyl pyridines | MERCK & CO., INC. (US) | 2007-09-18 | — | — | US | claimed |
| US-20050182103-A1 | Substituted 2,3-diphenyl pyridines | MERCK SHARP & DOHME CORP. | 2005-08-18 | — | — | US | claimed |
| EP-1492784-A2 | SUBSTITUTED 2,3-DIPHENYL PYRIDINES | Merck & Co., Inc. (US) | 2005-01-05 | — | — | EP | claimed |
| WO-2003082191-A2 | SUBSTITUTED 2,3-DIPHENYL PYRIDINES | MERCK & CO., INC. (US) | 2003-10-09 | — | — | WO | claimed |
| CN-116606200-A | Method for efficiently extracting menatetrenone in bacillus subtilis by combining ultrasonic vortex oscillation | 中国科学院合肥物质科学研究院 | 2023-08-18 | — | — | CN | disclosed |
| EP-4094268-A1 | SYSTEM AND METHOD FOR DATA-DRIVEN INDIVIDUALIZED NUTRITION | Loewi GmbH (DE) | 2022-11-30 | — | — | EP | disclosed |
| EP-3532480-B1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2020-11-25 | — | — | EP | disclosed |
| US-9520570-B2 | Organic electronic device and method for the production thereof | OSRAM OLED GMBH (DE) | 2016-12-13 | — | — | US | disclosed |
| US-9520570-B2 | Organic electronic device and method for the production thereof | OSRAM OLED GMBH (DE) | 2016-12-13 | — | — | US | disclosed |
| EP-2483945-B1 | ORGANIC ELECTRONIC DEVICE AND METHOD FOR THE PRODUCTION THEREOF | OSRAM OLED GMBH (DE) | 2016-11-02 | — | — | EP | disclosed |
| EP-2342772-B1 | ORGANIC ELECTRONIC COMPONENT AND METHOD FOR THE PRODUCTION THEREOF | OSRAM OLED GMBH (DE) | 2015-12-02 | — | — | EP | disclosed |
| US-8558223-B2 | Organic electronic component and method for the production thereof | OSRAM OPTO SEMICONDUCTORS GMBH (DE) | 2013-10-15 | — | — | US | disclosed |
| US-20110253991-A1 | ORGANIC ELECTROLUMINESCENCE DEVICE | NIPPON STEEL CHEMICAL CO., LTD. (JP) | 2011-10-20 | — | — | US | disclosed |
| EP-2378584-A1 | ORGANIC ELECTROLUMINESCENT ELEMENT | Pioneer Corporation (JP) | 2011-10-19 | — | — | EP | disclosed |
| WO-2011039323-A2 | ORGANIC ELECTRONIC DEVICE AND METHOD FOR THE PRODUCTION THEREOF | OSRAM OPTO SEMICONDUCTORS GMBH (DE) | 2011-04-07 | — | — | WO | disclosed |
| WO-2010034304-A2 | ORGANIC ELECTRONIC COMPONENT AND METHOD FOR THE PRODUCTION THEREOF | OSRAM OPTO SEMICONDUCTORS GMBH (DE) | 2010-04-01 | — | — | WO | disclosed |
| US-7271266-B2 | Substituted 2,3-diphenyl pyridines | MERCK & CO., INC. (US) | 2007-09-18 | — | — | US | disclosed |
| US-20050182103-A1 | Substituted 2,3-diphenyl pyridines | MERCK SHARP & DOHME CORP. | 2005-08-18 | — | — | US | disclosed |
| EP-1492784-A2 | SUBSTITUTED 2,3-DIPHENYL PYRIDINES | Merck & Co., Inc. (US) | 2005-01-05 | — | — | EP | disclosed |
| WO-2003082191-A2 | SUBSTITUTED 2,3-DIPHENYL PYRIDINES | MERCK & CO., INC. (US) | 2003-10-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050182103-A1 | Substituted 2,3-diphenyl pyridines | CNR1, CNR2, MAG | XDH 3302/4885LMNA 2024/4885ALOX15 452/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.