Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 5/20 | 0.33 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.30 |
| ▸ | CA2 | P00918 | 2/20 | 0.30 |
| ▸ | CA9 | Q16790 | 2/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5363639 | 0.85 | KDM4E (0.34) | KDM4EALDH1A1MAPTHPGDALOX15 | |
| SCHEMBL3148117 | 0.78 | P2RX7 (0.37) | P2RX7NOTUMCA1CA2CA9 | |
| SCHEMBL20745930 | 0.77 | P2RX7 (0.36) | MAPTALOX15MAPK1TDP1P2RX7 | |
| SCHEMBL3903645 | 0.74 | ALDH1A1 (0.58) | KDM4EALDH1A1MAPTHPGDALOX15 | |
| SCHEMBL15273739 | 0.67 | BCHE (0.34) | MAPTNOTUMCA1CA2CA9 | |
| SCHEMBL5357402 | 0.66 | P2RX7 (0.40) | KDM4EALDH1A1MAPTHPGDALOX15 | |
| SCHEMBL5357212 | 0.65 | TSHR (0.34) | KDM4EALDH1A1MAPK1TDP1 | |
| SCHEMBL7470953 | 0.64 | P2RX7 (0.53) | P2RX7NOTUMACSS2L3MBTL1 | |
| SCHEMBL3148070 | 0.62 | ALDH1A1 (0.41) | ALDH1A1 | |
| SCHEMBL2891146 | 0.62 | POLB (0.32) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007145349-A2 | SUBSTITUTED PYRROLE DERIVATIVES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-12-21 | — | — | WO | disclosed |