Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | ESR1 | P03372 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 3/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TYMS | P04818 | 1/20 | 0.36 |
| ▸ | ATIC | P31939 | 1/20 | 0.36 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.36 |
| ▸ | SUMO1 | P63165 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1548998 | 0.84 | MEN1 (0.71) | MEN1ESR1KMT2AESR2GAA | |
| SCHEMBL10935870 | 0.82 | CASP6 (0.50) | MEN1ESR1KMT2AESR2GAA | |
| SCHEMBL6111641 | 0.80 | MEN1 (0.56) | MEN1ESR1KMT2AESR2GAA | |
| SCHEMBL7783914 | 0.78 | GAA (0.57) | MEN1ESR1KMT2AESR2GAA | |
| SCHEMBL10712681 | 0.76 | PLAU (0.50) | GAAHTR6ALDH1A1KDM4EPLAU | |
| SCHEMBL29150913 | 0.75 | KMT2A (0.64) | MEN1ESR1KMT2AESR2GAA | |
| SCHEMBL6666097 | 0.75 | MEN1 (0.55) | MEN1ESR1KMT2AESR2GAA | |
| SCHEMBL15712827 | 0.72 | PLAU (0.46) | ALDH1A1PLAUHSD17B10 | |
| SCHEMBL6099899 | 0.72 | HTR6 (0.54) | MEN1ESR1KMT2AESR2GAA | |
| SCHEMBL27538787 | 0.71 | GAA (0.46) | MEN1ESR1KMT2AESR2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018202681-A1 | USE OF DISUBSTITUTED BENZENES TO CONTROL INSECTICIDE-RESISTANT PESTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-11-08 | — | — | WO | disclosed |
| US-7247756-B2 | 1,4-disubstituted benzenes as insecticides | BAYER CROPSCIENCE AG (DE) | 2007-07-24 | — | — | US | disclosed |
| US-6753429-B2 | FOR USE AS INSECTICIDES AGAINST A VARIETY OF INSECTS, INCLUDING LARVAE, SUCH AS TOBACCO BUDWORM | FMC CORPORATION | 2004-06-22 | — | — | US | disclosed |
| US-20030207894-A1 | 1,4-Disubstituted benzenes as insecticides | BAYER CROPSCIENCE AG (DE) | 2003-11-06 | — | — | US | disclosed |
| EP-1334083-A2 | 1,4-DISUBSTITUTED BENZENES AS INSECTICIDES | FMC CORPORATION (US) | 2003-08-13 | — | — | EP | disclosed |
| US-20020183342-A1 | 1,4-Disubstituted benzenes as insecticides | BAYER CROPSCIENCE AG (DE) | 2002-12-05 | — | — | US | disclosed |
| WO-2002017712-A2 | DISUBSTITUTED BENZENES AS INSECTICIDES | FMC CORPORATION (US) | 2002-03-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030207894-A1 | 1,4-Disubstituted benzenes as insecticides | DDT, CYP1B1, CYP4B1 | MEN1 3147/4885ESR1 2795/4885KMT2A 1607/4885 |
| US-20020183342-A1 | 1,4-Disubstituted benzenes as insecticides | DDT, CYP1B1, CYP4B1 | MEN1 3147/4885ESR1 2795/4885KMT2A 1607/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.