Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.40 |
| ▸ | TUBB | P07437 | 1/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1073454 | 0.83 | MEN1 (0.68) | MEN1KMT2AESR1GAAESR2 | |
| SCHEMBL5366484 | 0.80 | MEN1 (0.56) | MEN1KMT2AESR1GAAESR2 | |
| SCHEMBL28390792 | 0.80 | HTR6 (0.55) | MEN1KMT2AESR1GAAESR2 | |
| SCHEMBL15442508 | 0.78 | KMT2A (0.60) | MEN1KMT2AESR1GAAESR2 | |
| SCHEMBL10712681 | 0.77 | PLAU (0.50) | GAALMNAALDH1A1MAPTHTR6 | |
| SCHEMBL9131043 | 0.76 | LMNA (0.56) | MEN1KMT2AESR1GAAESR2 | |
| SCHEMBL31572327 | 0.76 | LMNA (0.56) | MEN1KMT2AESR1GAAESR2 | |
| SCHEMBL64533 | 0.76 | KMT2A (0.62) | MEN1KMT2AESR1GAAESR2 | |
| SCHEMBL14875638 | 0.76 | KMT2A (0.56) | MEN1KMT2AESR1GAAESR2 | |
| SCHEMBL13995003 | 0.75 | CYP1A2 (0.66) | MEN1KMT2AESR1GAAESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7247756-B2 | 1,4-disubstituted benzenes as insecticides | BAYER CROPSCIENCE AG (DE) | 2007-07-24 | — | — | US | disclosed |
| US-7247756-B2 | 1,4-disubstituted benzenes as insecticides | BAYER CROPSCIENCE AG (DE) | 2007-07-24 | — | — | US | disclosed |
| WO-2006078619-A1 | INSECTICIDAL HETEROCYCLIC 1,4-DISUBSTITUTED BENZENE N-OXIDES | BAYER CROPSCIENCE AG (DE) | 2006-07-27 | — | — | WO | disclosed |