SCHEMBL5367246

SCHEMBL5367246

CCOc1cc(S)c2n[c]sc2c1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.35
ALDH1A1 P00352 2/20 0.34
HSD17B10 Q99714 2/20 0.34
KMT2A Q03164 2/20 0.34
TP53 P04637 1/20 0.34
CYP3A4 P08684 1/20 0.34
TSHR P16473 1/20 0.34
PSMB8 P28062 1/20 0.32
NQO1 P15559 1/20 0.31
KDM4E B2RXH2 1/20 0.31
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
LMNA P02545 1/20 0.31
CA3 P07451 1/20 0.31
PKM P14618 1/20 0.31
CA4 P22748 1/20 0.31
CA6 P23280 1/20 0.31
CA5A P35218 1/20 0.31
CA7 P43166 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7574867 0.83 ALDH1A1 (0.38) MAPTALDH1A1HSD17B10KMT2ATP53
SCHEMBL11698158 0.81 MAPT (0.37) MAPTALDH1A1HSD17B10KMT2ATP53
SCHEMBL227271 0.71 KMT2A (0.53) MAPTALDH1A1HSD17B10KMT2ATP53
SCHEMBL7585003 0.71 KMT2A (0.35) MAPTALDH1A1KMT2ATP53KDM4E
SCHEMBL59017 0.70 MAPT (0.44) MAPTALDH1A1HSD17B10KMT2ATP53
SCHEMBL8361509 0.69 NPC1 (0.41) MAPTALDH1A1HSD17B10KMT2ATP53
SCHEMBL59019 0.69 MAPT (0.43) MAPTALDH1A1HSD17B10KMT2ATP53
SCHEMBL482247 0.68 ALDH1A1 (0.45) MAPTALDH1A1HSD17B10KMT2ATP53
SCHEMBL7577367 0.64 LMNA (0.37) ALDH1A1CYP3A4CA12CA1CA2
SCHEMBL11697332 0.64 ALDH1A1 (0.34) MAPTALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7166407-B2 Imaging element having protective overcoat layers EASTMAN KODAK COMPANY (US) 2007-01-23 US disclosed
US-20050084783-A1 Imaging element having protective overcoat layers FAR EAST DEVELOPMENT LTD. 2005-04-21 US disclosed