Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | TP53 | P04637 | 5/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.35 |
| ▸ | HBB | P68871 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA3 | P07451 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7585003 | 0.84 | KMT2A (0.35) | ALDH1A1TP53KMT2AKDM4EMAPT | |
| SCHEMBL11698158 | 0.83 | MAPT (0.37) | ALDH1A1TP53HSD17B10KMT2ACYP3A4 | |
| SCHEMBL5367246 | 0.83 | MAPT (0.35) | ALDH1A1TP53HSD17B10KMT2ACYP3A4 | |
| SCHEMBL227271 | 0.75 | KMT2A (0.53) | ALDH1A1TP53HSD17B10KMT2ACYP3A4 | |
| SCHEMBL557732 | 0.75 | ALDH1A1 (0.53) | ALDH1A1TP53HSD17B10KMT2AKDM4E | |
| SCHEMBL7577367 | 0.75 | LMNA (0.37) | ALDH1A1CYP3A4MAPK1LMNACA12 | |
| SCHEMBL482247 | 0.72 | ALDH1A1 (0.45) | ALDH1A1TP53HSD17B10KMT2ACYP3A4 | |
| SCHEMBL11459515 | 0.70 | ALDH1A1 (0.43) | ALDH1A1TP53HSD17B10KMT2ACYP3A4 | |
| SCHEMBL11697332 | 0.65 | ALDH1A1 (0.34) | ALDH1A1CYP3A4MAPTRXFP1CYP1A2 | |
| SCHEMBL6630377 | 0.64 | NQO1 (0.48) | ALDH1A1TP53HSD17B10KMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882730-B1 | PHOSPHONIC ACID DIESTER DERIVATIVES | OTSUKA PHARMA CO LTD (JP) | 2002-10-02 | — | — | EP | disclosed |
| US-5985858-A | TREATING AND PREVENTING HYPERLIPIDEMIA, DIABETES AND CATARACT, OR AS AN ANTITUMOR AGENT | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1999-11-16 | — | — | US | disclosed |
| EP-0882730-A1 | PHOSPHONIC ACID DIESTER DERIVATIVES | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1998-12-09 | — | — | EP | disclosed |