Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.53 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.41 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.41 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3606208 | 0.92 | TP53 (0.44) | MTNR1AMTNR1BPOLBEPHX2CDYL2 | |
| SCHEMBL5345354 | 0.87 | TRPA1 (0.44) | POLBTP53HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL5367265 | 0.83 | MTNR1A (0.52) | MTNR1AMTNR1BCDYL2CDYLCDY1; CDY1B | |
| SCHEMBL3602189 | 0.81 | HPGD (0.43) | POLBTP53HPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL3605823 | 0.81 | HTT (0.42) | POLBHPGDTSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL3597093 | 0.79 | BACE1 (0.47) | POLBEPHX2HPGDTSHRSMN1; SMN2 | |
| SCHEMBL3599702 | 0.78 | GRIN2B (0.41) | POLBTP53HPGDHSD17B10ALDH1A1 | |
| SCHEMBL3606205 | 0.76 | TP53 (0.45) | MTNR1AMTNR1BCDYL2CDYLCDY1; CDY1B | |
| SCHEMBL3644326 | 0.76 | KDM4E (0.48) | MTNR1AMTNR1BPOLBEPHX2HPGD | |
| SCHEMBL3605623 | 0.75 | TRPA1 (0.43) | POLBEPHX2HPGDSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007115231-A2 | CXCR4 MODULATORS | CHEMOCENTRYX, INC. (US) | 2007-10-11 | — | — | WO | disclosed |