Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 2/20 | 0.58 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.58 |
| ▸ | PPARG | P37231 | 2/20 | 0.54 |
| ▸ | OXER1 | Q8TDS5 | 8/20 | 0.50 |
| ▸ | CCR2 | P41597 | 1/20 | 0.49 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14386999 | 0.85 | AGTR1 (0.61) | AGTR1AGTR2PPARGOXER1CCR2 | |
| SCHEMBL7554153 | 0.79 | CCR2 (0.57) | AGTR1AGTR2PPARGOXER1CCR2 | |
| SCHEMBL5681564 | 0.75 | HPGD (0.59) | — | |
| SCHEMBL4392253 | 0.75 | HPGD (0.59) | — | |
| SCHEMBL30874195 | 0.75 | HPGD (0.59) | — | |
| SCHEMBL8165390 | 0.75 | HPGD (0.59) | — | |
| SCHEMBL932750 | 0.75 | HPGD (0.59) | — | |
| SCHEMBL287205 | 0.75 | OXER1 (0.69) | AGTR1AGTR2OXER1 | |
| SCHEMBL15700119 | 0.74 | AGTR1 (0.57) | AGTR1AGTR2PPARGCCR2 | |
| SCHEMBL11033108 | 0.74 | FAAH (0.63) | OXER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007134421-A1 | 2-VINYL INDOLES, PYRIDO AND AZEPINO INDOLE DERIVATIVES, 2-ALKYNYL INDOLES, 2-ALKYNYL BENZO[b]FURANS, THEIR PRECURSORS AND NOVEL PROCESSES FOR THE PREPARATION THEREOF | LAUTENS MARK (CA) | 2007-11-29 | — | — | WO | disclosed |
| WO-2007134421-A1 | 2-VINYL INDOLES, PYRIDO AND AZEPINO INDOLE DERIVATIVES, 2-ALKYNYL INDOLES, 2-ALKYNYL BENZO[b]FURANS, THEIR PRECURSORS AND NOVEL PROCESSES FOR THE PREPARATION THEREOF | LAUTENS MARK (CA) | 2007-11-29 | — | — | WO | disclosed |