Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.41 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.41 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.41 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 2/20 | 0.39 |
| ▸ | MPO | P05164 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5371032 | 0.89 | ALDH1A1 (0.47) | ALDH1A1POLBMEN1KMT2AKDM4E | |
| SCHEMBL5379284 | 0.88 | ALDH1A1 (0.46) | ALDH1A1POLBMEN1KMT2AKDM4E | |
| SCHEMBL5370125 | 0.87 | MPO (0.53) | ALDH1A1POLBKDM4EHSD17B10HTR6 | |
| SCHEMBL5371789 | 0.86 | HSD17B10 (0.46) | ALDH1A1POLBKMT2AKDM4EPIM1 | |
| SCHEMBL5334148 | 0.84 | POLB (0.44) | ALDH1A1POLBMEN1KMT2AKDM4E | |
| SCHEMBL5378982 | 0.84 | KDM4E (0.49) | ALDH1A1MEN1KMT2AKDM4EGAA | |
| SCHEMBL945973 | 0.80 | ALDH1A1 (0.65) | ALDH1A1POLBMEN1KMT2AKDM4E | |
| SCHEMBL5370003 | 0.79 | MPO (0.52) | ALDH1A1POLBKDM4EMPOPPARG | |
| SCHEMBL5328593 | 0.78 | ALDH1A1 (0.46) | ALDH1A1POLBMEN1KMT2AKDM4E | |
| SCHEMBL5333836 | 0.77 | HTR6 (0.52) | ALDH1A1POLBMEN1KMT2AHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007046112-A1 | ARYLTHIOETHER TRYPTAMINE DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS | SUVEN LIFE SCIENCES INC. (IN) | 2007-04-26 | — | — | WO | disclosed |