Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | SRD5A2 | P31213 | 4/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA3 | P07451 | 1/20 | 0.52 |
| ▸ | TYR | P14679 | 1/20 | 0.52 |
| ▸ | DRD1 | P21728 | 1/20 | 0.52 |
| ▸ | CA4 | P22748 | 1/20 | 0.52 |
| ▸ | CA6 | P23280 | 1/20 | 0.52 |
| ▸ | CA5A | P35218 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.52 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | DAO | P14920 | 1/20 | 0.50 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL11402475 | 0.83 | TSHR (0.35) | TSHRTP53CA1CA2CA9 | |
| SCHEMBL11238566 | 0.81 | SRD5A2 (0.50) | SRD5A2CA1CA2ALDH1A1 | |
| SCHEMBL29789030 | 0.81 | RARB (0.69) | TSHRTP53SRD5A2CA1CA2 | |
| SCHEMBL69572 | 0.81 | RARB (0.69) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL28240782 | 0.80 | TSHR (0.75) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL175823 | 0.80 | TSHR (1.00) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL2511919 | 0.80 | TSHR (1.00) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL5053781 | 0.80 | TSHR (1.00) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL1655 | 0.80 | TSHR (1.00) | TSHRTP53SRD5A2CA1CA2 | |
| Hydrochloric Acid SCHEMBL5666955 | 0.79 | RARB (0.67) | TSHRTP53SRD5A2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1308 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190031618-A1 | BENZIMIDAZOLE DERIVATIVES USEFUL AS CB-1 INVERSE AGONISTS | JANSSEN PHARMACEUTICA NV (BE) | 2019-01-31 | — | — | US | claimed |
| CN-106103463-B | Bridging type nucleosides and nucleotide | 国立大学法人大阪大学 | 2018-11-30 | — | — | CN | claimed |
| US-10118900-B2 | Benzimidazole derivatives useful as CB-1 inverse agonists | JANSSEN PHARMACEUTICA NV (BE) | 2018-11-06 | — | — | US | claimed |
| EP-3109254-B1 | CROSSLINKED NUCLEOSIDE AND NUCLEOTIDE | UNIV OSAKA (JP) | 2018-04-11 | — | — | EP | claimed |
| WO-2017035114-A1 | BENZIMIDAZOLE DERIVATIVES USEFUL AS CB-1 INVERSE AGONISTS | JANSSEN PHARMACEUTICA NV (BE) | 2017-03-02 | — | — | WO | claimed |
| US-20170057929-A1 | BENZIMIDAZOLE DERIVATIVES USEFUL AS CB-1 INVERSE AGONISTS | JANSSEN PHARMACEUTICA NV (BE) | 2017-03-02 | — | — | US | claimed |
| EP-2632576-B1 | METHOD FOR MAKING A COMPOSITE POLYAMIDE MEMBRANE | DOW GLOBAL TECHNOLOGIES LLC (US) | 2014-10-08 | — | — | EP | claimed |
| US-20140193752-A1 | STABILIZED ACID AMPLIFIERS | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2014-07-10 | — | — | US | claimed |
| US-8501382-B1 | Acid amplifiers | THE RESEARCH FOUNDATION OF STATE UNIV. OF NEW YORK (US) | 2013-08-06 | — | — | US | claimed |
| WO-2012135286-A2 | STABILIZED ACID AMPLIFIERS | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2012-10-04 | — | — | WO | claimed |
| EP-0724585-A1 | HYDANTOIN DERIVATIVES AND THEIR USE AS BLEACH ACTIVATORS | DEGUSSA (DE) | 1996-08-07 | — | — | EP | claimed |
| US-5504076-A | Cephalosporin compounds | PFIZER INC. (US) | 1996-04-02 | — | — | US | claimed |
| WO-1995014021-A1 | HYDANTOIN DERIVATIVES AND THEIR USE AS BLEACH ACTIVATORS | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1995-05-26 | — | — | WO | claimed |
| CN-1094035-A | Carboxylic acid derivative contains pharmaceutical composition of these compounds and preparation method thereof | THOMAE GMBH DR K (DE) | 1994-10-26 | — | — | CN | claimed |
| US-5266696-A | Colorfast dyes, dyeing, printing and dyed fibers | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-11-30 | — | — | US | claimed |
| US-5112971-A | ANTHRAQUINONE DYE COMPOUNDS HAVING FIBERS REACTIVE GROUP | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-05-12 | — | — | US | claimed |
| CN-1050023-A | The method for preparing cephalosporin derivative | BEECHAM GROUP PLC (GB) | 1991-03-20 | — | — | CN | claimed |
| EP-0416814-A2 | Cephalosporin compounds, process for their preparation, pharmaceutical compositions and intermediates | BEECHAM GROUP PLC (GB) | 1991-03-13 | — | — | EP | claimed |
| EP-0133225-B1 | PEPTIDE DERIVATIVES AND THEIR SALTS, PHARMACEUTICAL PREPARATIONS CONTAINING THEM, PROCESS AND INTERMEDIATES FOR THEIR PRODUCTION | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1988-10-19 | — | — | EP | claimed |
| US-4623639-A | ANTIINFLAMMATORY AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1986-11-18 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190031618-A1 | BENZIMIDAZOLE DERIVATIVES USEFUL AS CB-1 INVERSE AGONISTS | CNR1, GPR119, CNR2 | TSHR 777/4885TP53 4689/4885SRD5A2 1917/4885 |
| US-20170057929-A1 | BENZIMIDAZOLE DERIVATIVES USEFUL AS CB-1 INVERSE AGONISTS | CNR1, GPR119, CNR2 | TSHR 771/4885TP53 4685/4885SRD5A2 1894/4885 |
| US-10118900-B2 | Benzimidazole derivatives useful as CB-1 inverse agonists | CNR1, GPR119, CNR2 | TSHR 771/4885TP53 4685/4885SRD5A2 1894/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.