Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13732368 | 0.81 | ALOX5 (0.49) | POLBCTDSP1RAB9ANPC1KMT2A | |
| SCHEMBL16683909 | 0.80 | ALDH1A1 (0.47) | POLBCTDSP1RAB9ANPC1KMT2A | |
| SCHEMBL762539 | 0.80 | ALDH1A1 (0.47) | POLBCTDSP1RAB9ANPC1KMT2A | |
| SCHEMBL16683911 | 0.80 | ALDH1A1 (0.47) | POLBCTDSP1RAB9ANPC1KMT2A | |
| SCHEMBL18640588 | 0.78 | ALDH1A1 (0.46) | POLBCTDSP1RAB9ANPC1KMT2A | |
| SCHEMBL7355153 | 0.74 | RAB9A (0.43) | POLBCTDSP1RAB9ANPC1KMT2A | |
| SCHEMBL31561618 | 0.74 | NPC1 (0.46) | POLBCTDSP1RAB9ANPC1KMT2A | |
| SCHEMBL24479790 | 0.74 | RAB9A (0.48) | POLBRAB9ANPC1KMT2AGAA | |
| SCHEMBL1975525 | 0.74 | ALDH1A1 (0.53) | POLBRAB9ANPC1GAAHPGD | |
| SCHEMBL4418028 | 0.73 | ALOX5 (0.49) | POLBRAB9ANPC1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007047394-A2 | THIOTRIAZOLYL DERIVATIVES | EPIX DELAWARE, INC. (US) | 2007-04-26 | — | — | WO | claimed |
| WO-2007047394-A2 | THIOTRIAZOLYL DERIVATIVES | EPIX DELAWARE, INC. (US) | 2007-04-26 | — | — | WO | disclosed |