Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | POLB | P06746 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28037764 | 0.81 | RAB9A (0.48) | RAB9ANPC1ALDH1A1POLBHPGD | |
| SCHEMBL16683911 | 0.80 | ALDH1A1 (0.47) | RAB9ANPC1ALDH1A1POLBHPGD | |
| SCHEMBL16683909 | 0.80 | ALDH1A1 (0.47) | RAB9ANPC1ALDH1A1POLBHPGD | |
| SCHEMBL762539 | 0.80 | ALDH1A1 (0.47) | RAB9ANPC1ALDH1A1POLBHPGD | |
| SCHEMBL13732368 | 0.78 | ALOX5 (0.49) | RAB9ANPC1ALDH1A1POLBHPGD | |
| SCHEMBL18640588 | 0.78 | ALDH1A1 (0.46) | RAB9ANPC1ALDH1A1POLBHPGD | |
| Acrylic Acid SCHEMBL9562332 | 0.77 | RAB9A (0.40) | RAB9ANPC1ALDH1A1POLBHPGD | |
| SCHEMBL13388423 | 0.77 | ALDH1A1 (0.43) | RAB9ANPC1ALDH1A1POLBHPGD | |
| SCHEMBL5368294 | 0.74 | POLB (0.47) | RAB9ANPC1ALDH1A1POLBHPGD | |
| SCHEMBL31561618 | 0.74 | NPC1 (0.46) | RAB9ANPC1ALDH1A1POLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1112269-A2 | HIV PROTEASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 2001-07-04 | — | — | EP | disclosed |
| WO-2000015634-A2 | HIV PROTEASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 2000-03-23 | — | — | WO | disclosed |