SCHEMBL536830

SCHEMBL536830

[CH2]CCC(CC)c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.45
CCR5 P51681 1/20 0.42
TAAR1 Q96RJ0 4/20 0.38
CYP2D6 P10635 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
HRH1 P35367 5/20 0.38
HTR2A P28223 4/20 0.38
SIGMAR1 Q99720 1/20 0.37
MIF P14174 1/20 0.37
HKDC1 Q2TB90 1/20 0.36
TRPA1 O75762 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15061554 1.00 LMNA (0.45) LMNACCR5TAAR1CYP2D6MEN1
Ammonia Solution, Strong SCHEMBL27550294 0.98 LMNA (0.43) LMNACCR5TAAR1CYP2D6MEN1
SCHEMBL3385362 0.88 LMNA (0.42) LMNACCR5TAAR1CYP2D6HRH1
SCHEMBL4354924 0.86 HRH1 (0.42) LMNATAAR1CYP2D6HRH1HTR2A
SCHEMBL9869713 0.86 SIGMAR1 (0.42) LMNACCR5TAAR1CYP2D6HRH1
SCHEMBL3375650 0.85 AOC3 (0.42) LMNACCR5TAAR1HRH1HTR2A
SCHEMBL11099949 0.84 NR1I2 (0.44) LMNACCR5TAAR1CYP2D6HRH1
SCHEMBL17183751 0.84 NR1I2 (0.44) LMNACCR5TAAR1CYP2D6HRH1
SCHEMBL27567790 0.84 NR1I2 (0.44) LMNACCR5TAAR1CYP2D6HRH1
SCHEMBL17183686 0.84 NR1I2 (0.44) LMNACCR5TAAR1CYP2D6HRH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 517 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108211422-B Device and method for reducing caprolactam in benzene extraction raffinate 阳煤集团太原化工新材料有限公司 2024-04-26 CN disclosed
CN-113710637-B Preparation method of biaryl phosphine 日本化学工业株式会社 2023-10-24 CN disclosed
WO-2023182221-A1 METHOD FOR PRODUCING QUANTUM DOTS 日本化学工業株式会社 2023-09-28 WO disclosed
CN-111655708-B 2, 3-biphosphinopyrazine derivative, process for producing the same, complex compound, catalyst, and process for producing organoboron compound 日本化学工业株式会社 2023-08-25 CN disclosed
US-11718758-B2 Aqueous dispersion of colored particles MITSUBISHI PENCIL COMPANY, LIMITED (JP) 2023-08-08 US disclosed
EP-3725854-B1 COLORED PARTICLE AQUEOUS DISPERSION MITSUBISHI PENCIL CO (JP) 2023-07-05 EP disclosed
CN-111465662-B Aqueous dispersion of coloured particles 三菱铅笔株式会社 2023-05-26 CN disclosed
US-20230095021-A1 MODULATORS OF TDP-43 ALTERON THERAPEUTICS, LLC 2023-03-30 US disclosed
CN-111032668-B Optically active 2,3-bisphosphinylpyrazine derivative, process for producing the same, transition metal complex, and process for producing organoboron compound 日本化学工业株式会社 2022-10-14 CN disclosed
US-20220177509-A1 PRODUCTION OF BRIDGED ARTIFICIAL NUCLEOSIDES NIPPON SHOKUBAI CO., LTD. (JP) 2022-06-09 US disclosed
EP-0203722-A1 Bicyclic pyrazolidinones ELI LILLY AND COMPANY (US) 1986-12-03 EP disclosed
EP-0203723-A1 2,3-(dihydro)bicyclic pyrazolidinones ELI LILLY AND COMPANY (US) 1986-12-03 EP disclosed
EP-0202794-A1 7-Substituted-2,3-(Dihydro) bicyclic pyrazolidinones ELI LILLY AND COMPANY (US) 1986-11-26 EP disclosed
EP-0202047-A1 Pyrazolidinium ylides ELI LILLY AND COMPANY (US) 1986-11-20 EP disclosed
EP-0202046-A1 7-Substituted bicyclic pyrazolidinones ELI LILLY AND COMPANY (US) 1986-11-20 EP disclosed
CN-86102877-A The method for preparing bicyclic pyrazolidinones 1986-10-29 CN disclosed
US-4517002-A Phosphorodiamide urease inhibitors and urease inhibited urea based fertilizer compositions ALLIED CORPORATION (US) 1985-05-14 US disclosed
EP-0119494-A1 Urease inhibited urea based fertilizer compositions containing phosphorus compounds ALLIED CORPORATION (US) 1984-09-26 EP disclosed
US-3957928-A S-AMMONIUM-O-HYDROCARBYL-N-ACYL PHOSPHORAMIDOTHIOATE SALT PRODUCTION AND REACTION WITH ALKYLATING AGENT CHEVRON RESEARCH COMPANY (US) 1976-05-18 US disclosed
US-3931218-A HYPOGLYCEMIC ANTIRESERPINE, ANTIULCER, OGENIC, ANTIARRHYTHMIA AMERICAN HOME PRODUCTS CORPORATION (US) 1976-01-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230095021-A1 MODULATORS OF TDP-43 TARDBP, TDP1, TDP2 LMNA 388/4885CCR5 4039/4885TAAR1 4086/4885
US-20220177509-A1 PRODUCTION OF BRIDGED ARTIFICIAL NUCLEOSIDES TYMP, PNP, TYMS LMNA 2504/4885CCR5 3222/4885TAAR1 4089/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.