Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 4/20 | 0.43 |
| ▸ | CA9 | Q16790 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5305230 | 0.83 | KMT2A (0.44) | CA12CA9CA2CA1MAOA | |
| SCHEMBL3009674 | 0.68 | HPGD (0.59) | SMN1; SMN2POLBCA12CA9CA1 | |
| SCHEMBL94133 | 0.68 | POLB (0.59) | SMN1; SMN2POLBCA12CA9CA2 | |
| SCHEMBL29934196 | 0.68 | POLB (0.59) | SMN1; SMN2POLBCA12CA9CA2 | |
| SCHEMBL27625488 | 0.68 | MMP2 (0.67) | SMN1; SMN2POLBCA12CA9CA2 | |
| SCHEMBL13612673 | 0.68 | MAOA (0.61) | SMN1; SMN2POLBCA12CA9CA2 | |
| SCHEMBL3237487 | 0.67 | POLB (0.58) | SMN1; SMN2POLBCA12CA9CA2 | |
| SCHEMBL1619109 | 0.67 | MAOB (0.67) | SMN1; SMN2POLBCA12CA9CA1 | |
| SCHEMBL30594160 | 0.67 | MAOB (0.67) | SMN1; SMN2POLBCA12CA9CA1 | |
| SCHEMBL30311162 | 0.66 | MMP2 (0.60) | SMN1; SMN2POLBCA12CA9CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007012724-A1 | 1,2,4-THIADIAZOLE DERIVATIVES ANTIFUNGAL COMPOUNDS, COMPOSITIONS CONTAINING SAID COMPOUNDS AND THE USE THEREOF | CYTOMICS SYSTEMS (FR) | 2007-02-01 | — | — | WO | disclosed |