Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.41 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | SI | P14410 | 1/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MIF | P14174 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30385424 | 0.81 | TSHR (0.67) | TSHRMEN1KMT2ALMNAUSP2 | |
| SCHEMBL2002577 | 0.81 | TSHR (0.67) | TSHRMEN1KMT2ALMNAUSP2 | |
| SCHEMBL5369405 | 0.79 | ERCC5 (0.39) | MEN1KMT2ALMNAMAPTALDH1A1 | |
| SCHEMBL406193 | 0.79 | ERCC5 (0.59) | TSHRMEN1KMT2APOLBGAA | |
| SCHEMBL9720642 | 0.79 | MAPT (0.40) | TSHRKMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL17861210 | 0.78 | TSHR (0.52) | TSHRMEN1KMT2AGAAMGAM | |
| SCHEMBL32688037 | 0.78 | TSHR (0.52) | TSHRMEN1KMT2AUSP2MAPT | |
| SCHEMBL11772453 | 0.78 | NPC1 (0.53) | TSHRMEN1KMT2ALMNAMAPT | |
| SCHEMBL31388602 | 0.78 | TSHR (0.72) | TSHRKMT2ALMNAALDH1A1HSD17B10 | |
| SCHEMBL6678873 | 0.77 | ERCC5 (0.40) | MEN1KMT2ALMNAUSP2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050107455-A1 | Novel tricycloimidazoline derivatives method for production and use thereof as medicaments | PIERRE FABRE MEDICAMENT (FR) | 2005-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050107455-A1 | Novel tricycloimidazoline derivatives method for production and use thereof as medicaments | CYP4F3, HRH4, SLCO1B3 | TSHR 1396/4885MEN1 633/4885KMT2A 3902/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.