Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC5 | P28715 | 3/20 | 0.40 |
| ▸ | FEN1 | P39748 | 3/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | TGM2 | P21980 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5369405 | 0.84 | ERCC5 (0.39) | ERCC5FEN1PTPN1MAPTKMT2A | |
| SCHEMBL6342612 | 0.81 | CYP3A4 (0.40) | PTPN1MAPTKMT2AMEN1KDM4E | |
| SCHEMBL27612063 | 0.80 | ALDH1A1 (0.54) | MAPTKMT2AMEN1KDM4EHPGD | |
| SCHEMBL19971468 | 0.80 | MEN1 (0.46) | MAPTKMT2AMEN1KDM4ERAB9A | |
| SCHEMBL7515781 | 0.79 | ALDH1A1 (0.45) | MAPTKMT2AKDM4ERAB9ACYP3A4 | |
| SCHEMBL28713351 | 0.79 | CYP3A4 (0.39) | PTPN1KMT2AKDM4ECYP3A4HPGD | |
| SCHEMBL28169041 | 0.79 | CYP3A4 (0.43) | PTPN1MAPTKMT2AMEN1KDM4E | |
| SCHEMBL10623096 | 0.79 | PTPN1 (0.50) | PTPN1MAPTKDM4ECYP3A4HPGD | |
| SCHEMBL9720642 | 0.79 | MAPT (0.40) | MAPTKMT2AKDM4ECYP3A4HPGD | |
| SCHEMBL9356372 | 0.79 | ERCC5 (0.41) | ERCC5FEN1PTPN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1476433-A1 | NOVEL TRICYCLOIMIDAZOLINE DERIVATIVES, METHOD FOR PRODUCTION AND USE THEREOF AS MEDICAMENTS | PIERRE FABRE MEDICAMENT (FR) | 2004-11-17 | — | — | EP | disclosed |
| WO-2003068755-A1 | NOVEL TRICYCLOIMIDAZOLINE DERIVATIVES, METHOD FOR PRODUCTION AND USE THEREOF AS MEDICAMENTS | PIERRE FABRE MEDICAMENT (FR) | 2003-08-21 | — | — | WO | disclosed |