Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.49 |
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.46 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.46 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.46 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.74 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.74 |
| ▸ | TP53 | P04637 | 1/20 | 0.74 |
| ▸ | HTT | P42858 | 3/20 | 0.72 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.71 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 1/20 | 0.51 |
| ▸ | MC4R | P32245 | 1/20 | 0.51 |
| ▸ | RAD52 | P43351 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1485802 | 1.00 | MEN1 (0.74) | MEN1KMT2AMAPK1SMN1; SMN2TP53 | |
| Hydrochloric Acid SCHEMBL2812473 | 1.00 | MEN1 (0.74) | MEN1KMT2AMAPK1SMN1; SMN2TP53 | |
| Hydrochloric Acid SCHEMBL1123494 | 1.00 | MEN1 (0.74) | MEN1KMT2AMAPK1SMN1; SMN2TP53 | |
| Hydrochloric Acid SCHEMBL23494884 | 1.00 | MEN1 (0.74) | MEN1KMT2AMAPK1SMN1; SMN2TP53 | |
| Hydrochloric Acid SCHEMBL14877028 | 1.00 | MEN1 (0.74) | MEN1KMT2AMAPK1SMN1; SMN2TP53 | |
| Hydrochloric Acid SCHEMBL23494872 | 1.00 | MEN1 (0.74) | MEN1KMT2AMAPK1SMN1; SMN2TP53 | |
| Hydrochloric Acid SCHEMBL6233446 | 1.00 | MEN1 (0.74) | MEN1KMT2AMAPK1SMN1; SMN2TP53 | |
| Hydrochloric Acid SCHEMBL3027039 | 1.00 | MEN1 (0.74) | MEN1KMT2AMAPK1SMN1; SMN2TP53 | |
| Hydrochloric Acid SCHEMBL3029590 | 1.00 | MEN1 (0.74) | MEN1KMT2AMAPK1SMN1; SMN2TP53 | |
| Hydrochloric Acid SCHEMBL7632707 | 1.00 | MEN1 (0.74) | MEN1KMT2AMAPK1SMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140174737-A1 | Wellbore Servicing Materials and Methods of Making and Using Same | HALLIBURTON ENERGY SERVICES, INC. (US) | 2014-06-26 | — | — | US | claimed |
| WO-2014099616-A1 | WELLBORE SERVICING MATERIALS AND METHODS OF MAKING AND USING SAME | HALLIBURTON ENERGY SERVICES, INC. (US) | 2014-06-26 | — | — | WO | claimed |
| US-11898091-B2 | Synergistic blends of anti-agglomerant gas hydrate inhibitors with quaternary benzyl ammonium compounds | CLARIANT INTERNATIONAL LTD (CH) | 2024-02-13 | — | — | US | disclosed |
| US-11572499-B2 | Method of and a composition for controlling gas hydrate blockage through the addition of a synergistically acting blend with a quaternary benzyl ammonium compound | CLARIANT INTERNATIONAL LTD (CH) | 2023-02-07 | — | — | US | disclosed |
| EP-4073199-A1 | SYNERGISTIC BLENDS OF ANTI-AGGLOMERANT GAS HYDRATE INHIBITORS WITH QUATERNARY BENZYL AMMONIUM COMPOUNDS | Clariant International Ltd (CH) | 2022-10-19 | — | — | EP | disclosed |
| EP-4073197-A1 | A METHOD OF AND A COMPOSITION FOR CONTROLLING GAS HYDRATE BLOCKAGE THROUGH THE ADDITION OF A SYNERGISTICALLY ACTING BLEND WITH A QUATERNARY BENZYL AMMONIUM COMPOUND | Clariant International Ltd (CH) | 2022-10-19 | — | — | EP | disclosed |
| US-20210179919-A1 | Method Of And A Composition For Controlling Gas Hydrate Blockage Through The Addition Of A Synergistically Acting Blend With A Quaternary Benzyl Ammonium Compound | CLARIANT INTERNATIONAL, LTD. (CH) | 2021-06-17 | — | — | US | disclosed |
| WO-2021115969-A1 | SYNERGISTIC BLENDS OF ANTI-AGGLOMERANT GAS HYDRATE INHIBITORS WITH QUATERNARY BENZYL AMMONIUM COMPOUNDS | CLARIANT INTERNATIONAL LTD (CH) | 2021-06-17 | — | — | WO | disclosed |
| US-20210179918-A1 | Synergistic Blends Of Anti-Agglomerant Gas Hydrate Inhibitors With Quaternary Benzyl Ammonium Compounds | CLARIANT INTERNATIONAL, LTD. (CH) | 2021-06-17 | — | — | US | disclosed |
| WO-2021115970-A1 | A METHOD OF AND A COMPOSITION FOR CONTROLLING GAS HYDRATE BLOCKAGE THROUGH THE ADDITION OF A SYNERGISTICALLY ACTING BLEND WITH A QUATERNARY BENZYL AMMONIUM COMPOUND | CLARIANT INTERNATIONAL LTD (CH) | 2021-06-17 | — | — | WO | disclosed |
| CN-104093307-A | Method for controlling pests | KAO CORP | 2014-10-08 | — | — | CN | disclosed |
| US-20140174737-A1 | Wellbore Servicing Materials and Methods of Making and Using Same | HALLIBURTON ENERGY SERVICES, INC. (US) | 2014-06-26 | — | — | US | disclosed |
| WO-2014099621-A1 | WELLBORE SERVICING MATERIALS AND METHODS OF MAKING AND USING SAME | HALLIBURTON ENERGY SERVICES, INC. (US) | 2014-06-26 | — | — | WO | disclosed |
| US-7309452-B2 | Phenolate-containing formulation with low freezing point | OMYA DEVELOPMENT AG (CH) | 2007-12-18 | — | — | US | disclosed |
| US-6994798-B2 | Phenolate-containing formulation with low freezing point | OMYA AG (CH) | 2006-02-07 | — | — | US | disclosed |
| US-20040023939-A1 | Phenolates-containing formulation with low freezing point | OMYA DEVELOPMENT AG (CH) | 2004-02-05 | — | — | US | disclosed |
| EP-0519943-B1 | CLEANING AND DISINFECTING AGENT | HENKEL KGAA (DE) | 1995-01-11 | — | — | EP | disclosed |
| US-4348292-A | Multi-layered liquid detergent-builder concentrate compositions which on addition to water produce stable cleaning solutions | WALTON-MARCH, INC. (US) | 1982-09-07 | — | — | US | disclosed |
| US-4331447-A | ADDING AN OIL FRACTION AS A BINDER TO AN AQUEOUS SLURRY | SANYO CHEMICAL INDUSTRIES, LTD. (JP) | 1982-05-25 | — | — | US | disclosed |
| US-4096311-A | POST-TREATMENT OF ADDING WATER AND SURVACTANT, WET-WORKING | SCOTT PAPER COMPANY (US) | 1978-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11898091-B2 | Synergistic blends of anti-agglomerant gas hydrate inhibitors with quaternary benzyl ammonium compounds | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, RCC1, AQP1 | ACHE 2568/4885CHRM2 48/4885CHRM1 8/4885 |
| US-11572499-B2 | Method of and a composition for controlling gas hydrate blockage through the addition of a synergistically acting blend with a quaternary benzyl ammonium compound | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CHRM1, AQP1 | ACHE 2195/4885CHRM2 4/4885CHRM1 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.