Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 5/20 | 0.36 |
| ▸ | MMP13 | P45452 | 6/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 5/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MMP1 | P03956 | 4/20 | 0.33 |
| ▸ | ADAM17 | P78536 | 4/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5366593 | 0.83 | MAPK1 (0.51) | MAPK1TSHRRAPGEF3POLBGAA | |
| SCHEMBL5359135 | 0.81 | MAPK1 (0.39) | MAPK1RAPGEF3POLBLMNAALDH1A1 | |
| SCHEMBL5378086 | 0.77 | ALDH1A1 (0.35) | MMP13MMP1POLBGAALMNA | |
| SCHEMBL5446479 | 0.76 | BRS3 (0.37) | DYRK1ADGAT1PKMHPGDALDH1A1 | |
| SCHEMBL5370647 | 0.74 | ALDH1A1 (0.42) | MAPK1PKMPOLBGAAALDH1A1 | |
| SCHEMBL5364279 | 0.73 | DGAT1 (0.45) | DYRK1ADGAT1MMP13MMP9MMP1 | |
| SCHEMBL5362121 | 0.73 | LMNA (0.37) | MAPK1GAALMNAALDH1A1HTT | |
| SCHEMBL3881117 | 0.73 | DGAT1 (0.49) | DGAT1MAPK1GAALMNAALDH1A1 | |
| SCHEMBL5368104 | 0.69 | MAPK1 (0.50) | MAPK1PKMHPGDTSHRLMNA | |
| SCHEMBL5377787 | 0.69 | POLB (0.45) | HPGDTSHRPOLBGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7294716-B2 | Process for preparing isomerically pure prodrugs of proton pump inhibitors | ALLERGAN, INC. (US) | 2007-11-13 | — | — | US | disclosed |
| US-20050038076-A1 | Process for preparing isomerically pure prodrugs of proton pump inhibitors | ALEVIUM PHARMACEUTICALS, INC. | 2005-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050038076-A1 | Process for preparing isomerically pure prodrugs of proton pump inhibitors | SI, ATP6AP1, HRH2 | DYRK1A 2271/4885DGAT1 4563/4885MMP13 3547/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.