Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | CCL2 | P13500 | 1/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7197990 | 0.74 | HTR2A (0.38) | HTR2AHTR6CYP2D6BRD4CCL2 | |
| SCHEMBL1680359 | 0.74 | RET (0.38) | HTR2AHTR6CYP2D6BRD4CCL2 | |
| SCHEMBL5150447 | 0.74 | HTR2A (0.38) | HTR2AHTR6CYP2D6BRD4CCL2 | |
| SCHEMBL1680358 | 0.74 | HTR2A (0.38) | HTR2AHTR6CYP2D6BRD4CCL2 | |
| SCHEMBL6700611 | 0.73 | POLB (0.39) | HTR2AHTR6CYP2D6BRD4CCL2 | |
| SCHEMBL63929 | 0.73 | HTR2A (0.34) | HTR2AHTR6CYP2D6BRD4CCL2 | |
| SCHEMBL30931450 | 0.72 | POLB (0.38) | HTR2AHTR6CYP2D6RETKDM4E | |
| SCHEMBL29723819 | 0.71 | SLC6A2 (0.38) | HTR2AHTR6RET | |
| SCHEMBL8694188 | 0.70 | POLB (0.49) | HTR2AHTR6CYP2D6BRD4CCL2 | |
| SCHEMBL89374 | 0.70 | POLB (0.49) | HTR2AHTR6CYP2D6BRD4CCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005105777-A1 | SUBSTITUTED THIOPHENE AMIDE COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | PHARMACIA & UPJOHN COMPANY LLC (US) | 2005-11-10 | — | — | WO | claimed |
| US-20240027927-A1 | ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS | FUJIFILM BUSINESS INNOVATION CORP. (JP) | 2024-01-25 | — | — | US | disclosed |
| EP-4310593-A1 | ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS | FUJIFILM Business Innovation Corp. (JP) | 2024-01-24 | — | — | EP | disclosed |
| CN-117434803-A | Electrophotographic photoreceptor, process cartridge, and image forming apparatus | 富士胶片商业创新有限公司 | 2024-01-23 | — | — | CN | disclosed |
| US-20240012343-A1 | ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS | FUJIFILM BUSINESS INNOVATION CORP. (JP) | 2024-01-11 | — | — | US | disclosed |
| EP-4303660-A1 | ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS | FUJIFILM Business Innovation Corp. (JP) | 2024-01-10 | — | — | EP | disclosed |
| CN-117369230-A | Electrophotographic photoreceptor, process cartridge, and image forming apparatus | 富士胶片商业创新有限公司 | 2024-01-09 | — | — | CN | disclosed |
| US-20230333493-A1 | ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS | FUJIFILM BUSINESS INNOVATION CORP. (JP) | 2023-10-19 | — | — | US | disclosed |
| CN-116610010-A | Electrophotographic photoreceptor, process cartridge, and image forming apparatus | 富士胶片商业创新有限公司 | 2023-08-18 | — | — | CN | disclosed |
| CN-116610011-A | Electrophotographic photoreceptor, process cartridge, and image forming apparatus | 富士胶片商业创新有限公司 | 2023-08-18 | — | — | CN | disclosed |
| EP-2719688-A1 | Process for producing tetrazolyloxime derivatives | NIPPON SODA CO., LTD. (JP) | 2014-04-16 | — | — | EP | disclosed |
| EP-2719687-A1 | Process to make a bromopicoline derivative | NIPPON SODA CO., LTD. (JP) | 2014-04-16 | — | — | EP | disclosed |
| EP-2546236-A1 | COMPOUND CONTAINING PYRIDINE RING AND METHOD FOR PRODUCING HALOGENATED PICOLINE DERIVATIVE AND TETRAZOLYLOXIME DERIVATIVE | Nippon Soda Co., Ltd. (JP) | 2013-01-16 | — | — | EP | disclosed |
| US-20130012713-A1 | COMPOUND CONTAINING PYRIDINE RING AND METHOD FOR PRODUCING HALOGENATED PICOLINE DERIVATIVE AND TETRAZOLYLOXIME DERIVATIVE | NIPPON SODA CO., LTD | 2013-01-10 | — | — | US | disclosed |
| US-7217723-B2 | Substituted benzothiophenes, e.g., 7Z)-7-hydroxyimino-4,5,6,7-tetrahydro-benzo[b]thiophene-3-sulfonic acid [2-(4-fluorophenyl)-2-hydroxyethyl]-methyl-amide; treating allergies such as atopic dermatitis, allergic coryza, bronchial asthma, hypersensitive pneumoniac and pulmonary aspergillosis. | EISAI CO., LTD. (JP) | 2007-05-15 | — | — | US | disclosed |
| WO-2005105777-A1 | SUBSTITUTED THIOPHENE AMIDE COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | PHARMACIA & UPJOHN COMPANY LLC (US) | 2005-11-10 | — | — | WO | disclosed |
| US-20050227959-A1 | Heterocyclic compound having oxime group | EISAI CO., LTD. (JP) | 2005-10-13 | — | — | US | disclosed |
| US-6162828-A | IMMUNOLOGY; ANTIINFLAMMATORY AGENTS; ANTITUMOR AGENTS; BONE DISORDERS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2000-12-19 | — | — | US | disclosed |
| EP-0820464-A2 | CYSTEINE PROTEASE INHIBITOR | Takeda Chemical Industries, Ltd. (JP) | 1998-01-28 | — | — | EP | disclosed |
| WO-1996030395-A2 | CYSTEINE PROTEASE INHIBITOR | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-10-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130012713-A1 | COMPOUND CONTAINING PYRIDINE RING AND METHOD FOR PRODUCING HALOGENATED PICOLINE DERIVATIVE AND TETRAZOLYLOXIME DERIVATIVE | CBR3, PNPO, AADAC | HTR2A 3468/4885HTR6 892/4885CYP2D6 86/4885 |
| US-20050227959-A1 | Heterocyclic compound having oxime group | STAT6, HRH4, HRH2 | HTR2A 3002/4885HTR6 802/4885CYP2D6 326/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.