SCHEMBL5371895

SCHEMBL5371895

CCCC(C)OC(=O)C1CCC(C(=O)OC(C)CCC)CC1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 5/20 0.34
MAPT P10636 1/20 0.34
CTSL P07711 2/20 0.33
CTSB P07858 2/20 0.33
CTSK P43235 2/20 0.33
CNR1 P21554 1/20 0.33
CNR2 P34972 1/20 0.33
NAAA Q02083 1/20 0.33
CTSH P09668 1/20 0.33
CHRM1 P11229 2/20 0.33
CHRM3 P20309 2/20 0.33
ADRA1A P35348 2/20 0.33
CHRM2 P08172 1/20 0.33
CHRNA4 P43681 1/20 0.33
HTR3A P46098 1/20 0.33
KCNH2 Q12809 1/20 0.33
AKR1A1 P14550 1/20 0.32
HTR2A P28223 1/20 0.32
HTR2C P28335 1/20 0.32
HRH1 P35367 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5533200 0.91 ALDH1A1 (0.41) CTSLCTSBCTSKNAAACTSH
SCHEMBL10434986 0.88 CTSK (0.36) CTSLCTSBCTSKCTSHSMN1; SMN2
SCHEMBL21226095 0.88 GNAI3 (0.39) SLC6A3SMN1; SMN2
SCHEMBL15129692 0.87 FAAH (0.49) FAAHMAPTCTSKCNR1CNR2
SCHEMBL10845379 0.86 TLR4 (0.36) MAPTCTSLCTSBCTSKCTSH
SCHEMBL10845385 0.86 TLR4 (0.36) MAPTCTSLCTSBCTSKCTSH
SCHEMBL5364583 0.85 EPHX2 (0.39) FAAHCTSLCTSBCTSKCTSH
SCHEMBL5362719 0.85 FAAH (0.51) FAAHMAPTCTSKCNR1CNR2
SCHEMBL11824985 0.85 FAAH (0.51) FAAHMAPTCTSKCNR1CNR2
SCHEMBL10321962 0.83 ACACB (0.36) MAPTCTSLCTSBCTSKCTSH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7208545-B1 Selected cyclohexane -1,3-and -1,4-dicarboxylic acid esters BASF AKTIENGESELLSCHAFT (DE) 2007-04-24 US claimed
EP-1194396-B1 SELECTED CYCLOHEXANE-1,3- AND 1,4-DICARBOXYLIC ACID ESTERS BASF AG (DE) 2005-11-09 EP claimed
US-7208545-B1 Selected cyclohexane -1,3-and -1,4-dicarboxylic acid esters BASF AKTIENGESELLSCHAFT (DE) 2007-04-24 US disclosed