Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 1/20 | 0.47 |
| ▸ | LDHA | P00338 | 1/20 | 0.40 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | PPARD | Q03181 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7876161 | 0.89 | NR4A2 (0.48) | POLBTDP1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7872649 | 0.87 | EGFR (0.41) | MIFPOLBKDM4EHTTNPC1 | |
| SCHEMBL5372 | 0.81 | MIF (0.67) | MIFLDHACTBP2KDM4EHTT | |
| Phenylacetic Acid SCHEMBL7872638 | 0.78 | KDM4E (0.52) | MIFCTBP2POLBKDM4EPTGS1 | |
| SCHEMBL14013435 | 0.74 | MIF (0.43) | MIFPPARGPPARDPPARA | |
| SCHEMBL6895340 | 0.73 | MIF (0.56) | MIFLDHAKDM4EHTTSMN1; SMN2 | |
| SCHEMBL7872596 | 0.72 | RAB9A (0.52) | MIFPPARAPOLBKDM4EAKR1C3 | |
| SCHEMBL7867578 | 0.72 | RAB9A (0.52) | MIFPPARAPOLBKDM4EAKR1C3 | |
| Phenylacetic Acid SCHEMBL7876128 | 0.70 | KDM4E (0.43) | MIFCTBP2POLBKDM4EPTGS1 | |
| SCHEMBL7876137 | 0.70 | CYP3A4 (0.39) | FFAR1PPARGPPARDPPARATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6316623-B1 | USEFUL FOR SCREENING IN BIOLOGICAL ASSAYS IN ORDER TO IDENTIFY PHARMACEUTICALLY USEFUL COMPOUNDS | ISIS PHARMACEUTICALS, INC. | 2001-11-13 | — | — | US | disclosed |