Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | CMA1 | P23946 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL180328 | 0.87 | TAAR1 (0.43) | TAAR1SLC6A2SLC6A4SLC6A3HPGD | |
| SCHEMBL5381801 | 0.85 | TAAR1 (0.49) | TAAR1SLC6A2SLC6A4SLC6A3HPGD | |
| SCHEMBL20382761 | 0.85 | TAAR1 (0.44) | TAAR1SLC6A2SLC6A4SLC6A3HPGD | |
| SCHEMBL1292060 | 0.82 | TAAR1 (0.46) | TAAR1SLC6A2SLC6A4SLC6A3PARP1 | |
| SCHEMBL5372792 | 0.81 | GRIN2D (0.43) | TAAR1SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL5377511 | 0.80 | TAAR1 (0.47) | TAAR1SLC6A2SLC6A4SLC6A3HPGD | |
| SCHEMBL6570432 | 0.79 | TAAR1 (0.44) | TAAR1PARP1CMA1 | |
| SCHEMBL6567451 | 0.78 | PARP1 (0.57) | TAAR1SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL5386460 | 0.78 | TAAR1 (0.46) | TAAR1SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL1292108 | 0.78 | ALOX5 (0.46) | TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7235519-B2 | 1,2-substituted 2,3-dehydro-1H-5,9-dioxyacyclohepta[f]inden-7-ones and 7-substituted benzo[b]dioxepin-3-ones | GIVAUDAN SA (CH) | 2007-06-26 | — | — | US | claimed |
| US-20050288518-A1 | 1,2-Substituted 2,3-dehydro-1H-5,9-dioxyacyclohepta[f]inden-7-ones and 7-substituted benzo[b]dioxepin-3-ones | GIVAUDAN SA (CH) | 2005-12-29 | — | — | US | claimed |
| US-20030207788-A1 | 1,2 Substituted 2,3-dihydro- 1H-5,9 dioxacyclohepta[F]indden-7-ones and 7-substituted benzo[B][1,4]dioxepin-3 ones | GIVADUAN SA, CHEMIN DE LA PARFUMERIE (CH) | 2003-11-06 | — | — | US | claimed |
| EP-1136481-B1 | 1,2-Substituted 2,3-dihydro-1H-5,9-dioxacyclohepta[f]inden-7-ones and 7-substituted benzo[b][1,4]dioxepin-3-ones | GIVAUDAN SA (CH) | 2002-11-13 | — | — | EP | claimed |
| US-20010044407-A1 | Use in fragrance compositions; marine odor | GIVAUDAN SA (CH) | 2001-11-22 | — | — | US | claimed |
| EP-1136481-A1 | 1,2-Substituted 2,3-dihydro-1H-5,9-dioxacyclohepta[f]inden-7-ones and 7-substituted benzo[b][1,4]dioxepin-3-ones | Givaudan SA (CH) | 2001-09-26 | — | — | EP | claimed |
| US-7235519-B2 | 1,2-substituted 2,3-dehydro-1H-5,9-dioxyacyclohepta[f]inden-7-ones and 7-substituted benzo[b]dioxepin-3-ones | GIVAUDAN SA (CH) | 2007-06-26 | — | — | US | disclosed |
| US-7235519-B2 | 1,2-substituted 2,3-dehydro-1H-5,9-dioxyacyclohepta[f]inden-7-ones and 7-substituted benzo[b]dioxepin-3-ones | GIVAUDAN SA (CH) | 2007-06-26 | — | — | US | disclosed |
| US-7235519-B2 | 1,2-substituted 2,3-dehydro-1H-5,9-dioxyacyclohepta[f]inden-7-ones and 7-substituted benzo[b]dioxepin-3-ones | GIVAUDAN SA (CH) | 2007-06-26 | — | — | US | disclosed |
| US-7022664-B2 | 1,2 Substituted 2,3-dihydro-1H-5,9 dioxacyclohepta[F]indden-7-ones and 7-substituted benzo[B][1,4]dioxepin-3-ones | GIVAUDAN SA (CH) | 2006-04-04 | — | — | US | disclosed |
| EP-1405851-A1 | Method for producing seven-membered diether compounds and intermediates thereof | Takasago International Corporation (JP) | 2004-04-07 | — | — | EP | disclosed |
| US-20030207788-A1 | 1,2 Substituted 2,3-dihydro- 1H-5,9 dioxacyclohepta[F]indden-7-ones and 7-substituted benzo[B][1,4]dioxepin-3 ones | GIVADUAN SA, CHEMIN DE LA PARFUMERIE (CH) | 2003-11-06 | — | — | US | disclosed |
| EP-1136481-B1 | 1,2-Substituted 2,3-dihydro-1H-5,9-dioxacyclohepta[f]inden-7-ones and 7-substituted benzo[b][1,4]dioxepin-3-ones | GIVAUDAN SA (CH) | 2002-11-13 | — | — | EP | disclosed |
| US-20010044407-A1 | Use in fragrance compositions; marine odor | GIVAUDAN SA (CH) | 2001-11-22 | — | — | US | disclosed |
| EP-1136481-A1 | 1,2-Substituted 2,3-dihydro-1H-5,9-dioxacyclohepta[f]inden-7-ones and 7-substituted benzo[b][1,4]dioxepin-3-ones | Givaudan SA (CH) | 2001-09-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030207788-A1 | 1,2 Substituted 2,3-dihydro- 1H-5,9 dioxacyclohepta[F]indden-7-ones and 7-substituted benzo[B][1,4]dioxepin-3 ones | CYP1B1, CYP1A1, CYP4B1 | TAAR1 1988/4885SLC6A2 4823/4885SLC6A4 3826/4885 |
| US-20010044407-A1 | Use in fragrance compositions; marine odor | OPRD1, TRPA1, DBN1 | TAAR1 1432/4885SLC6A2 4856/4885SLC6A4 3968/4885 |
| US-20050288518-A1 | 1,2-Substituted 2,3-dehydro-1H-5,9-dioxyacyclohepta[f]inden-7-ones and 7-substituted benzo[b]dioxepin-3-ones | CYP1B1, CYP1A1, SULT1E1 | TAAR1 2549/4885SLC6A2 4802/4885SLC6A4 3650/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.