Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 14/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.62 |
| ▸ | DRD2 | P14416 | 14/20 | 0.58 |
| ▸ | DRD4 | P21917 | 9/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.58 |
| ▸ | HTR2A | P28223 | 7/20 | 0.58 |
| ▸ | HTR1A | P08908 | 7/20 | 0.56 |
| ▸ | HTR2C | P28335 | 4/20 | 0.56 |
| ▸ | DRD1 | P21728 | 3/20 | 0.56 |
| ▸ | HTR2B | P41595 | 3/20 | 0.56 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.56 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.56 |
| ▸ | HTR7 | P34969 | 2/20 | 0.56 |
| ▸ | HTR6 | P50406 | 2/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5263240 | 0.86 | DRD2 (0.62) | DRD3DRD2DRD4ADRA1AHTR2A | |
| SCHEMBL5262499 | 0.85 | DRD3 (0.44) | DRD3KCNH2DRD2DRD4ADRA1A | |
| SCHEMBL5265096 | 0.84 | HTR2A (0.43) | DRD3KCNH2DRD2ADRA1AHTR2A | |
| SCHEMBL5267672 | 0.83 | HTR2A (0.43) | DRD3KCNH2DRD2ADRA1AHTR2A | |
| SCHEMBL14339852 | 0.82 | DRD2 (0.64) | DRD3KCNH2DRD2DRD4HTR2A | |
| SCHEMBL5462058 | 0.81 | HTR2A (0.49) | DRD3KCNH2DRD2DRD4ADRA1A | |
| SCHEMBL14339848 | 0.77 | DRD3 (0.76) | DRD3KCNH2DRD2DRD4ADRA1A | |
| SCHEMBL21802150 | 0.74 | DRD3 (1.00) | DRD3KCNH2DRD2DRD4ADRA1A | |
| SCHEMBL8183795 | 0.73 | DRD3 (0.94) | DRD3KCNH2DRD2DRD4ADRA1A | |
| SCHEMBL14339849 | 0.73 | DRD3 (0.68) | DRD3KCNH2DRD2DRD4ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070299091-A1 | Azaindole Carboxamides | GMEINER PETER | 2007-12-27 | — | — | US | disclosed |
| US-20070299091-A1 | Azaindole Carboxamides | GMEINER PETER | 2007-12-27 | — | — | US | disclosed |
| EP-1771448-A1 | AZAINDOLE CARBOXAMIDES | SCHWARZ PHARMA AG (DE) | 2007-04-11 | — | — | EP | disclosed |
| WO-2006050976-A1 | AZAINDOLE CARBOXAMIDES | SCHWARZ PHARMA AG (DE) | 2006-05-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070299091-A1 | Azaindole Carboxamides | TPH1, TPH2, HTR1A | DRD3 176/4885KCNH2 1223/4885DRD2 64/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.