Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | PNP | P00491 | 6/20 | 0.45 |
| ▸ | HPRT1 | P00492 | 8/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Guanine SCHEMBL76053 | 0.95 | KDM4E (0.53) | KDM4EALDH1A1LMNAGLAPMP22 | |
| Guanine SCHEMBL663745 | 0.95 | KDM4E (0.53) | KDM4EALDH1A1LMNAGLAPMP22 | |
| Guanine SCHEMBL15948930 | 0.92 | KDM4E (0.50) | KDM4EALDH1A1LMNAGLAPMP22 | |
| Guanine SCHEMBL4658042 | 0.90 | ALDH1A1 (0.61) | KDM4EALDH1A1LMNAGLAPMP22 | |
| Guanine SCHEMBL5259 | 0.90 | ALDH1A1 (0.61) | KDM4EALDH1A1LMNAGLAPMP22 | |
| Guanine SCHEMBL101892 | 0.90 | KDM4E (0.48) | KDM4EALDH1A1LMNAGLAPMP22 | |
| Guanine SCHEMBL27542045 | 0.89 | HSD17B10 (0.56) | KDM4EALDH1A1LMNAGLAPMP22 | |
| Guanine SCHEMBL865492 | 0.89 | ALDH1A1 (0.59) | KDM4EALDH1A1LMNAGLAPMP22 | |
| Guanine SCHEMBL2895087 | 0.89 | ALDH1A1 (0.59) | KDM4EALDH1A1LMNAGLAPMP22 | |
| Guanine SCHEMBL21611717 | 0.89 | ALDH1A1 (0.59) | KDM4EALDH1A1LMNAGLAPMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7217523-B2 | Nucleoside phosphoramidates and nucleoside phosphoramidases | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2007-05-15 | — | — | US | claimed |
| US-20060014193-A1 | Nucleoside phosphoramidates and nucleoside phosphoramidases | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2006-01-19 | — | — | US | claimed |
| US-7217523-B2 | Nucleoside phosphoramidates and nucleoside phosphoramidases | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2007-05-15 | — | — | US | disclosed |
| US-20060014193-A1 | Nucleoside phosphoramidates and nucleoside phosphoramidases | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2006-01-19 | — | — | US | disclosed |