Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 6/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | HTR7 | P34969 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 2/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.43 |
| ▸ | CCR2 | P41597 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5372728 | 0.91 | KDM4E (0.51) | F10TP53CYP1A2TSHRPRSS1 | |
| SCHEMBL5371065 | 0.85 | EPHX2 (0.54) | F10CYP3A4PRSS1CCR2KDM4E | |
| SCHEMBL5372356 | 0.81 | F10 (0.60) | F10TP53CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL5164305 | 0.76 | F10 (0.79) | F10TSHRPRSS1RAB9AF2 | |
| SCHEMBL5368888 | 0.74 | F10 (0.44) | F10TP53CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL5371292 | 0.73 | F10 (0.98) | F10TP53CYP1A2CYP2D6TSHR | |
| SCHEMBL8975590 | 0.73 | RAB9A (0.80) | TP53CYP1A2CYP3A4CYP2D6TSHR | |
| SCHEMBL5372968 | 0.73 | TP53 (0.53) | F10TP53CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL5918522 | 0.73 | F10 (0.70) | F10PRSS1F2 | |
| SCHEMBL6784570 | 0.73 | F10 (0.49) | F10PRSS1F2CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040087582-A1 | Phenyl derivatives | MERCK PATENT GESELLSCHAFT (DE) | 2004-05-06 | — | — | US | claimed |
| US-7273867-B2 | Phenyl derivatives | MERCK PATENT GMBH (DE) | 2007-09-25 | — | — | US | disclosed |
| US-20040087582-A1 | Phenyl derivatives | MERCK PATENT GESELLSCHAFT (DE) | 2004-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040087582-A1 | Phenyl derivatives | F2, F11, SERPINC1 | F10 6/4885TP53 4035/4885CYP1A2 162/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.